Evidence map›Paper›PMID 25511010›Full record

ArticleLab on a chip2015

Nanostructured microfluidic digestion system for rapid high-performance proteolysis.

Gong Cheng, Si-Jie Hao, Xu Yu, Si-Yang Zheng

Abstract read
In one paragraph

Article in Lab on a chip, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gong ChengDepartment of Biomedical Engineering, The Pennsylvania State University, University Park, PA 16802, USA. sxz10@psu.edu.
Si-Jie Hao
Xu Yu
Si-Yang Zheng

Funding

Integration of Flexible Micro Spring Array and High Throughput Microfluidics forDP2CA174508 · NCI · PENNSYLVANIA STATE UNIVERSITY, THE · PI ZHENG, SIYANG · 2012 to 2012
$2.2M
NCI NIH HHS DP2 CA174508NCI NIH HHS DP2CA174508
6 · The paper itself

Abstract

A novel microfluidic protein digestion system with a nanostructured and bioactive inner surface was constructed by an easy biomimetic self-assembly strategy for rapid and effective proteolysis in 2 minutes, which is faster than the conventional overnight digestion methods. It is expected that this work would contribute to rapid online digestion in future high-throughput proteomics.

Indexed as

Lab-On-A-Chip DevicesProteolysisModels, MolecularNanostructuresParticle SizeSurface Properties

Identifiers

PMID25511010
PMCPMC4304898

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.