Evidence map›Paper›PMID 25510991›Full record

ArticleRevista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo2014

[Clinical, laboratorial and radiographic predictors of Bordetella pertussis infection].

Camila Vieira Bellettini, Andressa Welter de Oliveira, Cintia Tusset, Ludmila Fiorenzano Baethgen, Sérgio Luís Amantéa, Fabrizio Motta, Aline Gasparotto, Huander Felipe Andreolla, Alessandro C Pasqualotto

Open access · diamondAbstract read
In one paragraph

Article in Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. SEVERE PERTUSSIS IN CHILDHOOD: UPDATE AND CONTROVERSY - SYSTEMATIC REVIEW.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2019
    Pooled it
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  6. Critical pertussis infection in the paediatric intensive care unit: A case series in an outbreak.The Southern African journal of critical care : the official journal of the Critical Care Society · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Camila Vieira BellettiniUniversidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, RS, Brasil.
Andressa Welter de OliveiraUniversidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, RS, Brasil.
Cintia TussetUniversidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, RS, Brasil.
Ludmila Fiorenzano BaethgenUniversidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, RS, Brasil.
Sérgio Luís AmantéaIrmandade Santa Casa de Misericórdia de Porto Alegre, Porto Alegre, RS, Brasil.
Fabrizio MottaIrmandade Santa Casa de Misericórdia de Porto Alegre, Porto Alegre, RS, Brasil.
Aline GasparottoIrmandade Santa Casa de Misericórdia de Porto Alegre, Porto Alegre, RS, Brasil.
Huander Felipe AndreollaIrmandade Santa Casa de Misericórdia de Porto Alegre, Porto Alegre, RS, Brasil.
Alessandro C PasqualottoUniversidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, RS, Brasil; Irmandade Santa Casa de Misericórdia de Porto Alegre, Porto Alegre, RS, Brasil. Electronic address: acpasqualotto@hotmail.com.
Irmandade da Santa Casa de Misericórdia de São Paulo · BRUniversidade Federal de Ciências da Saúde de Porto Alegre · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo identify clinical, laboratorial and radiographic predictors for Bordetella pertussis infection.

methodsThis was a retrospective study, which analyzed medical records of all patients submitted to a molecular diagnosis (qPCR) for B. pertussis from September 2011 to January 2013. Clinical and laboratorial data were reviewed, including information about age, sex, signs/symptoms, length of hospitalization, blood cell counts, imaging findings, coinfection with other respiratory pathogens and clinical outcome.

results222 cases were revised. Of these, 72.5% had proven pertussis, and 60.9% were under 1 year old. In patients aging up to six months, independent predictors for B. pertussis infection were cyanosis (OR 8.0, CI 95% 1.8-36.3; p=0.007) and lymphocyte count >10(4)/μL (OR 10.0, CI 95% 1.8-54.5; p=0.008). No independent predictors of B. pertussis infection could be determined for patients older than six months. Co-infection was found in 21.4% of patients, of which 72.7% were up to six months of age. Adenovirus was the most common agent (40.9%). In these patients, we were not able to identify any clinical features to detect patients presenting with a respiratory co-infection, even though longer hospital stay was observed in patients with co-infections (12 vs. 6 days; p=0.009).

conclusionsCyanosis and lymphocytosis are independent predictors for pertussis in children up to 6 months old.

Indexed as

AdolescentAdultChildChild, PreschoolClinical Laboratory TechniquesFemaleHumansInfantInfant, NewbornMaleMiddle AgedPredictive Value of TestsRadiographyRetrospective StudiesWhooping CoughYoung AdultBordetella pertussisCoinfecçãoCoinfectionCoquelucheInfecçãoInfectionWhooping cough

Identifiers

PMID25510991
PMCPMC4311781
OpenAlexW1743521608

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.