ReviewInternational dental journal2015
Antibiotics in dental practice: how justified are we.
Review in International dental journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06164509 (Healing Potentiality of Different Doses of Trypsin and Alpha Chemo Trypsin in Mandibular Molars With Chronic Apical Abscess), which is not on this map. Cited by 85 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Healing Potentiality of Different Doses of Trypsin and Alpha Chemo Trypsin in Mandibular Molars With Chronic Apical Abscess
Who cites it
85 citing papers in PubMed, 202 citations in OpenAlex.
- Efficacy of clindamycin compared with amoxicillin-metronidazole after a 7-day regimen in the treatment of periodontitis in patients with diabetes: a randomized clinical trial.BMJ open diabetes research & care · 2020Trial
- Trial
- Comparison of two combinations of opioid and non-opioid analgesics for acute periradicular abscess: a randomized clinical trial.Journal of applied oral science : revista FOBTrial
- Knowledge, Attitudes, and Practices of Antibiotic Prescribing Among Arab Dental Students: A Cross-Sectional Study.International dental journal · 2026Article
- Antibiotic Prescribing Patterns and Antimicrobial Stewardship Among Indian Periodontists: A Cross-Sectional Survey.Healthcare (Basel, Switzerland) · 2026Article
- Reassessing Antibiotic Duration in Dental Infections: A Narrative Review and Marginal Benefit-Harm Framework with a Clinical Checklist.Antibiotics (Basel, Switzerland) · 2026Review
- Article
- Antibiotics for Prophylaxis of Infective Endocarditis in Pediatric Patients: Knowledge and Prescribing Practices Between Italian Dentists.Antibiotics (Basel, Switzerland) · 2026Article
- Evaluation of dental practitioners' knowledge and attitudes regarding drug interactions: a cross-sectional survey.BMC oral health · 2026Article
- A Thorough Analysis of Changing Antibiotic Resistance in Dental Practice: A Narrative Review.Cureus · 2026Review
- Article
- Development of Biocompatible Fatty Acid-Based Ionic Liquids for the Effective Topical Treatment of Periodontitis.ACS omega · 2026Article
- The dental implant surface: a review of the past, present and future.Journal of materials science. Materials in medicine · 2026Review
- Dental devices and antimicrobial resistance: challenges, innovations, and regulatory compliances.Frontiers in medical technology · 2026Review
- Prevalence and Predictors of Inappropriate Antibiotic Prescriptions Among Dentists in Muscat Governorate, Oman.Sultan Qaboos University medical journal · 2026Article
- Antimicrobial resistance in dental unit waterlines: a scoping review of microbial diversity, resistance patterns, and knowledge gaps.Frontiers in oral health · 2026Review
- Rational antibiotic prescribing practices among dentists in Turkey: a cross-sectional study.BMC oral health · 2025Article
- Costs-Outcome Description Arising From Side Effects due the Over-Prescription of Antibiotics in Oral Healthcare in Chile.Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology · 2025Article
- A Systematic Review on Prior/Postoperative Antibiotics Therapy Efficiency in Reducing Surgical Complications After Third Molar Extraction Surgery.Journal of maxillofacial and oral surgery · 2025Review
- Expert consensus on the treatment of oral diseases in pregnant women and infants.International journal of oral science · 2025Review
25 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Antibiotics are prescribed by dentists in dental practice, during dental treatment as well as for prevention of infection. Indications for the use of systemic antibiotics in dentistry are limited because most dental and periodontal diseases are best managed by operative intervention and oral hygiene measures. The use of antibiotics in dental practice is characterised by empirical prescription based on clinical and bacteriological epidemiological factors, resulting in the use of a very narrow range of broad-spectrum antibiotics for short periods of time. This has led to the development of antimicrobial resistance (AMR) in a wide range of microbes and to the consequent inefficacy of commonly used antibiotics. Dentists can make a difference by the judicious use of antimicrobials--prescribing the correct drug, at the standard dosage and appropriate regimen--only when systemic spread of infection is evident. The increasing resistance problems of recent years are probably related to the over- or misuse of broad-spectrum agents. There is a clear need for the development of prescribing guidelines and educational initiatives to encourage the rational and appropriate use of drugs in dentistry. This paper highlights the need for dentists to improve antibiotic prescribing practices in an attempt to curb the increasing incidence of antibiotic resistance and other side effects of antibiotic abuse. The literature provides evidence of inadequate prescribing practices by dentists for a number of factors, ranging from inadequate knowledge to social factors.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.