Evidence map›Paper›PMID 25510889›Full record

SynthesisBMJ open2014

Effect of rapid HIV testing on HIV incidence and services in populations at high risk for HIV exposure: an equity-focused systematic review.

Kevin Pottie, Olanrewaju Medu, Vivian Welch, Govinda P Dahal, Mark Tyndall, Tamara Rader, George Wells

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMJ open, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. The Effectiveness and Cost-Effectiveness of Screening for HIV in Migrants in the EU/EEA: A Systematic Review.International journal of environmental research and public health · 2018
    Pooled it
  4. Pooled it
  5. Article
  6. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2023
    Article
  7. Article
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  13. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2022
    Article
  14. Article
  15. Recommendations for equitable COVID-19 pandemic recovery in Canada.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2021
    Article
  16. Article
  17. Article
  18. Article
  19. An overview of reviews on strategies to reduce health inequalities.International journal for equity in health · 2020
    Review
  20. The contribution of HIV point-of-care tests in early HIV diagnosis: community-based HIV testing monitoring in Catalonia, 1995 to 2018.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kevin PottieDepartment of Family Medicine, University of Ottawa, Ottawa, Ontario, Canada Centre for Global Health, Institute of Population Health, University of Ottawa, Ottawa, Ontario, Canada Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, Ontario, Canada Bruyere Research Institute, Bruyere Continuing Care Ottawa Hospital Research Institute, The Ottawa Hospital.
Olanrewaju MeduDepartment of Epidemiology and Community Medicine, University of Ottawa, Ottawa, Ontario, Canada.
Vivian WelchCentre for Global Health, Institute of Population Health, University of Ottawa, Ottawa, Ontario, Canada Bruyere Research Institute, Bruyere Continuing Care Division of Infectious Disease, Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada University of Ottawa Heart Institute, University of Ottawa, Ottawa, Ontario, Canada.
Govinda P DahalCentre for Global Health, Institute of Population Health, University of Ottawa, Ottawa, Ontario, Canada Canada Foundation for Nepal, Ottawa, Ontario, Canada.
Mark TyndallDepartment of Epidemiology and Community Medicine, University of Ottawa, Ottawa, Ontario, Canada Bruyere Research Institute, Bruyere Continuing Care.
Tamara RaderCentre for Global Health, Institute of Population Health, University of Ottawa, Ottawa, Ontario, Canada.
George WellsDepartment of Epidemiology and Community Medicine, University of Ottawa, Ottawa, Ontario, Canada Ottawa Hospital Research Institute, The Ottawa Hospital.

Funding

Canadian Institutes of Health Research
6 · The paper itself

Abstract

objectiveTo assess the effects of rapid voluntary counselling and testing (VCT) for HIV on HIV incidence and uptake of HIV/AIDS services in people at high risk for HIV exposure.

designCochrane systematic review and meta-analysis. DATA SOURCES: We searched PubMed, EMBASE, AIDSearch, LILACS, Global Health, Medline Africa, PsychInfo, CINAHL, Cochrane CENTRAL, Cochrane HIV/AIDS Group Specialized Register and grey literature from 1 January 2001 to 5 June 2014 without language restriction. DATA SELECTION: We included controlled studies that compared rapid VCT with conventional testing among people at risk for HIV exposure. DATA EXTRACTION: Two reviewers extracted data. We used Cochrane risk of bias tool and GRADE criteria: risk of bias, inconsistency, indirectness, imprecision and publication bias. For observational studies we used the Newcastle-Ottawa Scale. We used the PRISMA-Equity reporting guideline.

resultsFrom 2441 articles, we included 8 randomised controlled trials and 5 observational studies. Rapid VCT was associated with a threefold increase in HIV-testing uptake (relative risk (RR)=2.95 95% CI 1.69 to 5.16) and a twofold increase in the receipt of test results (RR=2.14, 95% CI 1.08 to 4.24). Women accepted testing more often than men in rapid VCT arm, but no differences in effect for age or socioeconomic status. Observational studies also showed rapid VCT led to higher rates of uptake of testing. Heterogeneity was high. A cluster-randomised trial reported an 11% reduction in HIV incidence in intervention communities (RR=0.89, 95% CI=0.63 to 1.24) over 3 years trial.

conclusionsRapid VCT in health facilities and communities was associated with a large increase in HIV-testing uptake and receipt of results. This has implications for WHO guidelines. The routine use of rapid VCT may also help avoid human rights violations among marginalised populations where testing may occur without informed consent and where existing stigma may create barriers to testing.

Indexed as

HIVPatient Acceptance of Health CareCounselingDelayed DiagnosisHIV InfectionsHumansMass ScreeningRiskHIV ServicesHIV TestingRapid VCT

Identifiers

PMID25510889
PMCPMC4267075

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.