ArticleSpinal cord2015
Identification and treatment of sleep-disordered breathing in chronic spinal cord injury.
Article in Spinal cord, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prevalence of sleep-disordered breathing in people with tetraplegia-a systematic review and meta-analysis.Spinal cord · 2021Pooled it
- Sleep-disordered breathing is associated with brain vascular reactivity in spinal cord injury.Neurology · 2019Pooled it
- Trial
- Mirtazapine reduces susceptibility to hypocapnic central sleep apnea in males with sleep-disordered breathing: a pilot study.Journal of applied physiology (Bethesda, Md. : 1985) · 2021Trial
- Buspirone decreases susceptibility to hypocapnic central sleep apnea in chronic SCI patients.Journal of applied physiology (Bethesda, Md. : 1985) · 2020Trial
- Sleep apnea in individuals with spinal cord injury.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025Article
- Screening Strategies for Sleep-Disordered Breathing in Patients With Spinal Cord Injury in a Tertiary Care Rehabilitation Center.Respiratory care · 2024Article
- Prevalences of sleep-related breathing disorders and severity factors in chronic spinal cord injury and abled-bodied individuals undergoing rehabilitation: a comparative study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024Article
- Adherence to continuous positive airway pressure therapy in patients with spinal cord injury and obstructive sleep apnea: trajectories and predictors.Sleep & breathing = Schlaf & Atmung · 2024Article
- Association between sleep quality and participation in people with spinal cord injury: A preliminary study.The journal of spinal cord medicine · 2023Article
- Tetraplegia is associated with increased hypoxic ventilatory response during nonrapid eye movement sleep.Physiological reports · 2022Article
- Response to "Sleep quality and participation in patients with spinal cord injury".The journal of spinal cord medicine · 2022Article
- Protocol-Specific Effects of Intermittent Hypoxia Pre-Conditioning on Phrenic Motor Plasticity in Rats with Chronic Cervical Spinal Cord Injury.Journal of neurotrauma · 2021Article
- Understanding the clinical management of obstructive sleep apnoea in tetraplegia: a qualitative study using the theoretical domains framework.BMC health services research · 2019Article
- Sleep Complaints and Sleep Quality in Spinal Cord Injury: A Web-Based Survey.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2019Article
- Observational
- Review
- Impact Of Spinal Cord Injury On Sleep: Current Perspectives.Nature and science of sleep · 2019Article
- Article
- Nocturnal swallowing and arousal threshold in individuals with chronic spinal cord injury.Journal of applied physiology (Bethesda, Md. : 1985) · 2018Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
STUDY
designA follow up on an ongoing prospective cohort study.
objectiveSpinal cord injury or disorder (SCI/D) patients have higher rates of sleep-disordered breathing (SDB) than the general population. The objectives of this study were to examine predictors of SDB diagnosis and to estimate rates of SDB treatment in SCI/D patients.
settingA SCI clinical sleep research laboratory.
methodsTwenty-eight SCI/D patients (7 women, age 42.8 ± 15.8 years; 16 cervical and 12 thoracic level injuries) completed a battery of questionnaires (Epworth Sleepiness Scale (ESS), Pittsburgh Sleep Quality Index (PSQI), Berlin questionnaire (BQ) and fatigue severity scale (FSS)) and had one night of attended laboratory polysomnography (PSG). Participants were then notified of the results of their PSG and were interviewed approximately 1 year later to assess clinical outcomes.
resultsThe majority of patients reported poor sleep quality on all questionnaires. On the basis of PSG, 22 (79%) patients had SDB (apnea-hypopnea index (AHI)⩾ 5 events per hour), and 17 (61%) had moderate/severe SDB (AHI⩾15 events per hour). Higher ESS scores were associated with a higher risk of AHI ⩾ 5; however, other questionnaires did not distinguish between those with and without SDB using either AHI cutoff. In follow-up interviews, only 50% of patients had spoken to a health-care provider about SDB and only six patients with SDB were prescribed treatment, four of whom were using the treatment at follow-up.
conclusionSDB is common and severe among SCI/D patients. Screening questionnaires do not appear to differentiate between those with and without SDB. Even when SDB was recognized, many patients remained untreated. The increased prevalence of cardiovascular disease in SCI/D patients could represent a consequence of untreated SDB, and improving diagnosis and management of SDB has the potential to improve outcomes for these patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.