Evidence map›Paper›PMID 25506604›Full record

ArticleNeurobiology of stress2015

Targeting the Neuropeptide Y System in Stress-related Psychiatric Disorders.

Nicole M Enman, Esther L Sabban, Paul McGonigle, Elisabeth J Van Bockstaele

Open access · hybridAbstract read
In one paragraph

Article in Neurobiology of stress, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 1 synthesis or guideline pooled it, 123 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. D[HisPsychopharmacology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Neuropeptide Y and Pain: Insights from Brain Research.ACS pharmacology & translational science · 2024
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Nicole M EnmanDepartment of Pharmacology and Physiology, Drexel University, Philadelphia, PA, 19102, USA.
Esther L SabbanDepartment of Biochemistry and Molecular Biology, New York Medical College, Valhalla, NY, 10595, USA.
Paul McGonigleDepartment of Pharmacology and Physiology, Drexel University, Philadelphia, PA, 19102, USA.
Elisabeth J Van BockstaeleDepartment of Pharmacology and Physiology, Drexel University, Philadelphia, PA, 19102, USA.
New York Medical College · US

Funding

OPIOID MODULATION OF THE COERULEO-CORTICAL PATHWAYR01DA009082 · NIDA · THOMAS JEFFERSON UNIVERSITY · PI VAN BOCKSTAELE, ELISABETH J · 2001 to 2017
$6.0M
NIDA NIH HHS R01 DA009082
6 · The paper itself

Abstract

Repeated, extreme, or traumatic stressors can elicit pathological effects leading to many negative physical and psychological outcomes. Stressors can precipitate the onset of psychiatric diseases, or exacerbate pre-existing disorders including various anxiety and mood disorders. As stressors can negatively impact human psychiatric health, it is essential to identify neurochemicals that may confer protection from the negative sequelae of repeated or extreme stress exposure. Elucidating the neurobiological underpinnings of stress resilience will enhance our ability to promote resilience to, or recovery from, stress-related psychiatric disease. Herein, we will review the evidence for neuropeptide Y as an endogenous mediator of resilience and its potential relevance for the treatment of stress-related psychiatric diseases.

Indexed as

emotionalityneuropeptide Yrodent modelsstress-related psychiatric disordersstress resilience

Identifiers

PMID25506604
PMCPMC4260418
OpenAlexW2014415629

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.