Evidence map›Paper›PMID 25506462›Full record

ArticleJournal of addiction2014

Correlates and Consequences of Opioid Misuse among High-Risk Young Adults.

Sheree M Schrager, Aleksandar Kecojevic, Karol Silva, Jennifer Jackson Bloom, Ellen Iverson, Stephen E Lankenau

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of addiction, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Association between spine injury and opioid misuse in a prospective cohort of Level I trauma patients.OTA international : the open access journal of orthopaedic trauma · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sheree M SchragerDivision of Hospital Medicine, Children's Hospital Los Angeles, 4650 Sunset Boulevard, MS No. 94, Los Angeles, CA 90027, USA.
Aleksandar KecojevicDivision of Health Promotion and Behavioral Science, Graduate School of Public Health, San Diego State University, 9245 Sky Park Court, Suite 100, San Diego, CA 92123, USA.ORCID 0000-0003-4331-9161
Karol SilvaDepartment of Psychology, Temple University, 1801 N Broad Street, Philadelphia, PA 19122, USA.
Jennifer Jackson BloomDivision of Adolescent Medicine, Children's Hospital Los Angeles, 5000 Sunset Boulevard, Los Angeles, CA 90027, USA.
Ellen IversonDivision of Adolescent Medicine, Children's Hospital Los Angeles, 5000 Sunset Boulevard, Los Angeles, CA 90027, USA ; Department of Pediatrics, Keck School of Medicine, University of Southern California, 1975 Zonal Avenue, Los Angeles, CA 90089, USA.
Stephen E LankenauDepartment of Community Health and Prevention, School of Public Health, Drexel University, 1505 Race Street, Philadelphia, PA 19102, USA.

Funding

Non-Medical Prescription Drug Use Among High-Risk YouthR01DA021299 · NIDA · DREXEL UNIVERSITY · PI LANKENAU, STEPHEN E · 2007 to 2010
$2.4M
NIDA NIH HHS R01 DA021299
6 · The paper itself

Abstract

Background. Prescription opioids are the most frequently misused class of prescription drug among young adults aged 18-25, yet trajectories of opioid misuse and escalation are understudied. We sought to model opioid misuse patterns and relationships between opioid misuse, sociodemographic factors, and other substance uses. Methods. Participants were 575 young adults age 16-25 who had misused opioids in the last 90 days. Latent class analysis was performed with models based on years of misuse, recency of misuse, and alternate modes of administration within the past 12 months, 3 months, and 30 days. Results. Four latent classes emerged that were differentially associated with heroin, cocaine, and methamphetamine use, tranquilizer misuse, daily opioid misuse, and opioid withdrawal. Alternate modes of administering opioids were associated with increased risk for these outcomes. Sociodemographic factors, homelessness, prescription history, and history of parental drug use were significantly associated with riskier opioid misuse trajectories. Conclusion. Young adults who reported more debilitating experiences as children and adolescents misused opioids longer and engaged in higher risk alternate modes of administering opioids. Data on decisions both to use and to alter a drug's form can be combined to describe patterns of misuse over time and predict important risk behaviors.

Identifiers

PMID25506462
PMCPMC4259139

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.