Evidence map›Paper›PMID 25506415›Full record

ArticleAnnali di stomatologia2014

Histological evaluation of a biomimetic material in bone regeneration after one year from graft.

Michele M Figliuzzi, Rossella De Fazio, Rosamaria Tiano, Serena De Franceschi, Delfina Pacifico, Francesco Mangano, Leonzio Fortunato

Abstract read
In one paragraph

Article in Annali di stomatologia, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Michele M FigliuzziDepartment of Periodontics and Oral Sciences, Magna Graecia University, Catanzaro, Italy.
Rossella De FazioDepartment of Periodontics and Oral Sciences, Magna Graecia University, Catanzaro, Italy.
Rosamaria TianoDepartment of Periodontics and Oral Sciences, Magna Graecia University, Catanzaro, Italy.
Serena De FranceschiDepartment of Periodontics and Oral Sciences, Magna Graecia University, Catanzaro, Italy.
Delfina PacificoDepartment of Periodontics and Oral Sciences, Magna Graecia University, Catanzaro, Italy.
Francesco ManganoDepartment of Biomaterials, Insubria University, Varese, Italy.
Leonzio FortunatoDepartment of Periodontics and Oral Sciences, Magna Graecia University, Catanzaro, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe use of substitute materials is one of the solutions used in periodontology for the reconstruction of intrabony defects. Advances in scientific research gave rise to a new generation of biomaterials of synthetic origin stoichiometrically unstable and therefore really absorbable. Our research is directed precisely towards a biomaterial synthesis, Engipore® (Finceramica, Faenza, Italy) which is a bone substitute of the latest hydroxyapatite-based generation, that possesses chemical and morphological properties similar to those of natural bone in the treatment of infrabony periodontal defects. Aim of this study was to evaluate the efficacy of Engipore® in the treatment of intrabony periodontal defects.

methodsThe study was conducted on 100 parodontopatics patients, which had gingival pockets of at least infrabonies 8/10 mm. The histological evaluation was performed with samples after one year from the graft.

resultsThe histological samples collected after one year showed an abundant new bone formation, with mature lamellar bone tissue surrounding the residual particles of Engipore® that appear completely osteointegrated. The surrounding connective tissue shows no signs of inflammation.

conclusionsThe results obtained in our research demonstrated that, after a proper selection of patients and lesions, and applying an adequate surgical technique, this type of biomaterial in the treatment of periodontal defects acts in an optimal manner as a filler inducing the formation of new bone as evidenced by histological examinations.

Indexed as

biomimetic materialbone regenerationintrabony defectsperiosteum

Identifiers

PMID25506415
PMCPMC4252859

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