ArticleAdvanced functional materials2014
DNA Hybridization-Mediated Liposome Fusion at the Aqueous Liquid Crystal Interface.
Article in Advanced functional materials, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 37 citations in OpenAlex.
- From Population Averaging to Single Event Resolution: Evolution of Sensing Platforms for Membrane Fusion.Sensors (Basel, Switzerland) · 2026Review
- Liquid crystal-aqueous interface renders selective detection of distinct mycobacterial cell envelope responses.Journal of materials chemistry. B · 2025Article
- DNA-Programmed Lipid Nanoreactors for Synthesis of Carbohydrate Mimetics by Fusion of Aqueous Sub-attoliter Compartments.Journal of the American Chemical Society · 2023Article
- DNA-Modified Liquid Crystal Droplets.Biosensors · 2022Article
- Review
- Controlled Peptide-Mediated Vesicle Fusion Assessed by Simultaneous Dual-Colour Time-Lapsed Fluorescence Microscopy.Scientific reports · 2020Article
- Sensing of cocaine using polarized optical microscopy by exploiting the conformational changes of an aptamer at the water/liquid crystal interface.Mikrochimica acta · 2019Article
- Design and Application of Stimulus-Responsive Droplets and Bubbles Stabilized by Phospholipid Monolayers.Current opinion in colloid & interface science · 2019Article
- Artificial Membrane Fusion Triggered by Strain-Promoted Alkyne-Azide Cycloaddition.Bioconjugate chemistry · 2017Article
- The Assembly of DNA Amphiphiles at Liquid Crystal-Aqueous Interface.Nanomaterials (Basel, Switzerland) · 2016Article
- Design of Responsive and Active (Soft) Materials Using Liquid Crystals.Annual review of chemical and biomolecular engineering · 2016Review
- Mutually-Reactive, Fluorogenic Hydrocyanine/Quinone Reporter Pairs for In-Solution Biosensing via Nanodroplet Association.ACS applied materials & interfaces · 2016Article
- On-demand droplet fusion: a strategy for stimulus-responsive biosensing in solution.Langmuir : the ACS journal of surfaces and colloids · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
The prominence of receptor-mediated bilayer fusion in cellular biology motivates development of biomimetic strategies for studying fusogenic mechanisms. An approach is reported here for monitoring receptor-mediated fusion that exploits the unique physical and optical properties of liquid crystals (LC). PEG-functionalized lipids are used to create an interfacial environment capable of inhibiting spontaneous liposome fusion with an aqueous/LC interface. Then, DNA hybridization between oligonucleotides within bulk phase liposomes and a PEG-lipid monolayer at an aqueous/LC interface is exploited to induce receptor-mediated liposome fusion. These hybridization events induce strain within the liposome bilayer, promote lipid mixing with the LC interface, and consequently create an interfacial environment favoring re-orientation of the LC to a homeotropic (perpendicular) state. Furthermore, the bi-functionality of aptamers is exploited to modulate DNA hybridization-mediated liposome fusion by regulating the availability of the appropriate ligand (i.e., thrombin). Here, a LC-based approach for monitoring receptor (i.e., DNA hybridization)-mediated liposome fusion is demonstrated, liposome properties that dictate fusion dynamics are explored, and an example of how this approach may be used in a biosensing scheme is provided.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.