Evidence map›Paper›PMID 25506288›Full record

ArticleThe Yale journal of biology and medicine2014

Heart block and acute kidney injury due to hyperparathyroidism-induced hypercalcemic crisis.

Taylor C Brown, James M Healy, Mary J McDonald, Joni H Hansson, Courtney E Quinn

Abstract readCase Reports
In one paragraph

Article in The Yale journal of biology and medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Primary Hyperparathyroidism Is Associated With Shorter QTc Intervals, but Not Arrhythmia.The Journal of clinical endocrinology and metabolism · 2022
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Taylor C BrownDepartment of Surgery, Section of Endocrine Surgery, Yale School of Medicine, New Haven, Connecticut.
James M HealyDepartment of Surgery, Section of Endocrine Surgery, Yale School of Medicine, New Haven, Connecticut.
Mary J McDonaldDepartment of Pathology, Yale School of Medicine, New Haven, Connecticut.
Joni H HanssonDepartment of Internal Medicine, Section of Nephrology, Yale School of Medicine, New Haven, Connecticut.
Courtney E QuinnDepartment of Surgery, Section of Endocrine Surgery, Yale School of Medicine, New Haven, Connecticut.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe a patient who presented with multi-system organ failure due to extreme hypercalcemia (serum calcium 19.8 mg/dL), resulting from primary hyperparathyroidism. He was found to have a 4.8 cm solitary atypical parathyroid adenoma. His course was complicated by complete heart block, acute kidney injury, and significant neurocognitive disturbances. Relevant literature was reviewed and discussed. Hyperparathyroidism-induced hypercalcemic crisis (HIHC) is a rare presentation of primary hyperparathyroidism and only a small minority of these patients develop significant cardiac and renal complications. In cases of HIHC, a multidisciplinary effort can facilitate rapid treatment of life-threatening hypercalcemia and definitive treatment by surgical resection. As such, temporary transvenous cardiac pacing and renal replacement therapy can provide a life-saving bridge to definitive parathyroidectomy in cases of HIHC.

Indexed as

Acute Kidney InjuryAgedHeart BlockHumansHypercalcemiaHyperparathyroidismMaleParathyroid NeoplasmsUltrasonographyacute kidney injuryheart blockhypercalcemic crisishyperparathyroidism

Identifiers

PMID25506288
PMCPMC4257040

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.