ArticleJournal of conservative dentistry : JCD2014
Investigate the correlation between clinical sign and symptoms and the presence of P. gingivalis, T. denticola, and T. forsythia individually or as a "Red complex" by a multiplex PCR method.
Article in Journal of conservative dentistry : JCD, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 12 citations in OpenAlex.
- Microbiota-based Signature of Gingivitis Treatments: A Randomized Study.Scientific reports · 2016Trial
- Is apical periodontitis a matter of microbial diversity or time? A scoping review.Head & face medicine · 2026Article
- Use of pus metagenomic next-generation sequencing for efficient identification of pathogens in patients with sepsis.Folia microbiologica · 2024Article
- Association of specific microorganisms with endodontic signs and symptoms. A comparative study.Journal of family medicine and primary care · 2020Article
- Endodontic-Like Oral Biofilms as Models for Multispecies Interactions in Endodontic Diseases.Microorganisms · 2020Article
- Detection of Red complex bacteria,Journal of family medicine and primary care · 2020Article
- Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimThe aim of this study was to investigate the correlation between endodontic clinical signs and symptoms and the presence of Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia or their association by Multiplex polymerase chain reaction assay. MATERIALS AND
methodsMicrobial samples were taken from 30 cases with necrotic pulp tissues in primary infections. DNA was extracted from the samples, which were analyzed for the presence of three endodontic pathogens by using species-specific primers.
resultsP. gingivalis, T. denticola, T. forsythia, and Red Complex were present in 11, 17, 4, and 2 canals, respectively. Clinical and statistically significant relationships were found between T. forsythia and mobility and between T. denticola and swelling. (P < 0.05). Presence of other Red complex bacteria shows clinical association with presence of signs and symptoms but no statistically significant relationship.
conclusionThe high prevalence of P. gingivalis, T. denticola, and T. forsythia in the examined samples suggests that these bacteria are related to the etiology of symptomatic periradicular diseases.
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Registered trials
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