Evidence map›Paper›PMID 25505823›Full record

ReviewMediators of inflammation2014

Mushrooms: a potential natural source of anti-inflammatory compounds for medical applications.

Elsayed A Elsayed, Hesham El Enshasy, Mohammad A M Wadaan, Ramlan Aziz

Abstract readReview
In one paragraph

Review in Mediators of inflammation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

79 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Effects ofInternational journal of molecular sciences · 2018
    Pooled it
  2. Nutritional Mushroom Treatment in Meniere's Disease withInternational journal of molecular sciences · 2019
    Trial
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Anti-Inflammatory Mechanisms ofJournal of microbiology and biotechnology · 2025
    Article
  11. Review
  12. Nutritional and Therapeutic Potential ofJournal of fungi (Basel, Switzerland) · 2025
    Review
  13. Review
  14. Decoding the Tissue-Specific Profiles of Bioactive Compounds inJournal of fungi (Basel, Switzerland) · 2025
    Article
  15. Article
  16. Article
  17. Edible mushroom (Anatomy & cell biology · 2024
    Article
  18. Article
  19. Review
  20. Review

19 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Elsayed A ElsayedBioproducts Research Chair, Zoology Department, Faculty of Science, King Saud University, Riyadh 11451, Saudi Arabia ; Natural and Microbial Products Department, National Research Centre, Dokki, Cairo 12311, Egypt.
Hesham El EnshasyInstitute of Bioproduct Development (IBD), Universiti Teknologi Malaysia (UTM), 81130 Skudai, Malaysia ; City of Scientific Research and Technology Application, New Burg Al Arab, Alexandria 21934, Egypt.
Mohammad A M WadaanBioproducts Research Chair, Zoology Department, Faculty of Science, King Saud University, Riyadh 11451, Saudi Arabia.
Ramlan AzizInstitute of Bioproduct Development (IBD), Universiti Teknologi Malaysia (UTM), 81130 Skudai, Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For centuries, macrofungi have been used as food and medicine in different parts of the world. This is mainly attributed to their nutritional value as a potential source of carbohydrates, proteins, amino acids, and minerals. In addition, they also include many bioactive metabolites which make mushrooms and truffles common components in folk medicine, especially in Africa, the Middle East, China, and Japan. The reported medicinal effects of mushrooms include anti-inflammatory effects, with anti-inflammatory compounds of mushrooms comprising a highly diversified group in terms of their chemical structure. They include polysaccharides, terpenoids, phenolic compounds, and many other low molecular weight molecules. The aims of this review are to report the different types of bioactive metabolites and their relevant producers, as well as the different mechanisms of action of mushroom compounds as potent anti-inflammatory agents.

Indexed as

AgaricalesAnimalsAnti-Inflammatory AgentsCell LineFungiHumansInflammationInhibitory Concentration 50MiceModels, ChemicalMolecular ConformationPeptidesPolysaccharidesSignal TransductionAnti-Inflammatory AgentsPeptidesPolysaccharides

Identifiers

PMID25505823
PMCPMC4258329

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.