Evidence map›Paper›PMID 25505669›Full record

ReviewInternational journal of bipolar disorders2013

European Network of Bipolar Research Expert Centre (ENBREC): a network to foster research and promote innovative care.

Chantal Henry, Ole A Andreassen, Angelo Barbato, Jacques Demotes-Mainard, Guy Goodwin, Marion Leboyer, Eduard Vieta, Willem A Nolen, Lars Vedel Kessing, Jan Scott and 2 more

Abstract readReview
In one paragraph

Review in International journal of bipolar disorders, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. The efficacy of Li in bipolar disorder.Neuropsychiatric disease and treatment · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Chantal HenryUniversité Paris-Est, UMR_S955, UPEC, F-94000 Créteil, France ; Inserm, U955, Equipe Psychiatrie Génétique, F-94000 Créteil, France ; AP-HP, Hôpital H. Mondor - A. Chenevier, Pôle de Psychiatrie, F-94000 Créteil, France ; Fondation FondaMental, fondation de coopération scientifique, F-94000 Créteil, France.
Ole A AndreassenKG Jebsen Centre for Psychosis Research, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Angelo BarbatoLaboratory of Epidemiology and Social Psychiatry, Mario Negri Institute for Pharmacological Research, Milan, Italy.
Jacques Demotes-MainardEuropean Clinical Research Infrastructures Network (ECRIN), INSERM, Paris, France.
Guy GoodwinUniversity Department of Psychiatry, University of Oxford, Oxford, UK.
Marion LeboyerUniversité Paris-Est, UMR_S955, UPEC, F-94000 Créteil, France ; Inserm, U955, Equipe Psychiatrie Génétique, F-94000 Créteil, France ; AP-HP, Hôpital H. Mondor - A. Chenevier, Pôle de Psychiatrie, F-94000 Créteil, France ; Fondation FondaMental, fondation de coopération scientifique, F-94000 Créteil, France.
Eduard VietaInstitute of Neuroscience, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, ENBREC, Barcelona, Catalonia Spain.
Willem A NolenDepartment of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Lars Vedel KessingPsychiatric Center Copenhagen Department, Faculty of Health Sciences, University of Copenhagen, O 6233, Blegdamsvej 9, 2100 Copenhagen, Denmark.
Jan ScottAcademic Psychiatry, Institute of Neuroscience, Newcastle University, Newcastle-upon-Tyne, UK.
Michael BauerDepartment of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universität, Dresden, Germany.
ENBREC study group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bipolar disorders rank as one of the most disabling illnesses in working age adults worldwide. Despite this, the quality of care offered to patients with this disorder is suboptimal, largely due to limitations in our understanding of the pathology. Improving this scenario requires the development of a critical mass of expertise and multicentre collaborative projects. Within the framework of the European FP7 programme, we developed a European Network of Bipolar Research Expert Centres (ENBREC) designed specifically to facilitate EU-wide studies. ENBREC provides an integrated support structure facilitating research on disease mechanisms and clinical outcomes across six European countries (France, Germany, Italy, Norway, Spain and the UK). The centres are adopting a standardised clinical assessment that explores multiple aspects of bipolar disorder through a structured evaluation designed to inform clinical decision-making as well as being applicable to research. Reliable, established measures have been prioritised, and instruments have been translated and validated when necessary. An electronic healthcare record and monitoring system (e-ENBREC©) has been developed to collate the data. Protocols to conduct multicentre clinical observational studies and joint studies on cognitive function, biomarkers, genetics, and neuroimaging are in progress; a pilot study has been completed on strategies for routine implementation of psycho-education. The network demonstrates 'proof of principle' that expert centres across Europe can collaborate on a wide range of basic science and clinical programmes using shared protocols. This paper is to describe the network and how it aims to improve the quality and effectiveness of research in a neglected priority area.

Indexed as

Bipolar disorderClinical practiceResearch networksStandards of care

Identifiers

PMID25505669
PMCPMC4230652

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.