Evidence map›Paper›PMID 25505642›Full record

ArticleBone research

Subclinical Indication of Linkage Between Markers of Skeletal and Cardiovascular Properties.

Lynae J Hanks, Ambika P Ashraf, Barbara A Gower, Jessica A Alvarez, Krista Casazza

Open access · bronzeAbstract read
In one paragraph

Article in Bone research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 87% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Lynae J HanksDepartment of Nutrition Sciences, University of Alabama at Birmingham, Alabama, USA.
Ambika P AshrafChildren's of Alabama, University of Alabama at Birmingham, Alabama, USA.
Barbara A GowerDepartment of Nutrition Sciences, University of Alabama at Birmingham, Alabama, USA.
Jessica A AlvarezDivision of Endocrinology, Diabetes & Lipids, Emory University School of Medicine, Georgia, USA.
Krista CasazzaDepartment of Nutrition Sciences, University of Alabama at Birmingham, Alabama, USA.
University of Alabama at Birmingham · USEmory University · US

Funding

UAB CENTER FOR CLINICAL AND TRANSLATIONAL SCIENCE (CCTS) UL1: BPCAUL1RR025777 · NCRR · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GUAY-WOODFORD, LISA MARIE · 2008 to 2011
$22.3M
UAB Diabetes Research and Training CenterP60DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GARVEY, W TIMOTHY · 2008 to 2012
$8.4M
TRAINING IN CELLULAR PHYSIOLOGY MEMBRANE TRANSPORTT32DK007545 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GUTIERREZ, ORLANDO M · 1987 to 2023
$4.5M
Pediatric Physician Training in Translational ResearchK12HD043397 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI STAGNO, SERGIO BRUNO · 2003 to 2012
$3.4M
ENDOCRINOLOGY, METABOLISM, AND DIABETEST32DK007298 · NIDDK · EMORY UNIVERSITY · PI PACIFICI, ROBERTO · 1986 to 2014
$3.2M
NCRR NIH HHS UL1 RR025777NICHD NIH HHS K12 HD043397NIDDK NIH HHS P60 DK079626NIDDK NIH HHS T32 DK007298NIDDK NIH HHS T32 DK007545
6 · The paper itself

Abstract

Little is known about early coincidental changes in bone and vascular properties, particularly in the context of skeletal anabolism (puberty) versus relative equilibrium (young adulthood). We aimed to determine if subclinical markers of vascular function were associated with bone mineral content (BMC) and to evaluate the contribution of systemic factors in healthy females ages 14-42 years. Endothelial function was assessed by flow mediated dilatation (FMD), arterial stiffness by pulse wave velocity (PWV) and augmentation index (AIx), blood pressure (BP) by sphygmomanometer, BMC by DXA, and systemic factors by fasting blood draw. General linear models controlled for age, race and height indicated a positive association between systolic BP (SBP) and BMC independent of systemic factors. When stratified by age using 19 years as a cut-point, there was an inverse relationship between AIx75 in adolescents with insulin (

Indexed as

arterial stiffnessbone mineral contentendothelial functionsystolic blood pressure

Identifiers

PMID25505642
PMCPMC4259044
OpenAlexW2049305134

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.