ReviewFrontiers in microbiology2014
Biosynthesis of archaeal membrane ether lipids.
Review in Frontiers in microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers.
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Who cites it
92 citing papers in PubMed, 205 citations in OpenAlex.
- Review
- ACAD10 encodes two orphan enzymes in the ether lipid biosynthetic and salvage pathways.bioRxiv : the preprint server for biology · 2026Article
- Protocell formation on micrometeorites.Scientific reports · 2026Article
- In-sewer microplastics drive microbial metabolic shifts toward enhanced methanogenesis.Environmental science and ecotechnology · 2026Article
- Mysterious giants in the world of lipids: long linear isoprenoid functions in plant physiology and reproduction.Journal of experimental botany · 2026Review
- The potential of plant-derived triterpenoids as biological nitrification inhibitors.Applied microbiology and biotechnology · 2026Article
- Hypothesizing the Biotherapeutic Potential of Nitrosotalea devanaterra: Targeting Ammonia Dependency to Disrupt Helicobacter pylori Survival Strategies in Gastritis.The Eurasian journal of medicine · 2026Article
- Intracellular accumulation of hydrophobic 1,3-PDN inhibits methanogenesis in rumen methanogens.The ISME journal · 2026Article
- Biotechnological Applications of Archaea.Progress in molecular and subcellular biology · 2026Review
- Membrane changes during syntrophic interactions of an archaeal-bacterial coculture.BMC microbiology · 2025Article
- Beyond Methane Oxidation: The Protein Landscape of ANME-2a Reveals an Integrated System for Diazotrophy and Membrane Fortification.Environmental microbiology reports · 2025Article
- Marine Cold Seep ANME-2/SRB Consortia Produce Their Lipid Biomass From Inorganic Carbon.Environmental microbiology · 2025Article
- A dominant subgroup of marine Bathyarchaeia assimilates organic and inorganic carbon into unconventional membrane lipids.Nature microbiology · 2025Article
- Transcriptional landscape of the cell cycle in a model thermoacidophilic archaeon reveals similarities to eukaryotes.Nature communications · 2025Article
- Production of the Sesquiterpene Bisabolene From One- and Two-Carbon Compounds in Engineered Methanosarcina acetivorans.Microbial biotechnology · 2025Article
- Extreme thermal environments: reservoirs of industrially important thermozymes.Frontiers in microbiology · 2025Review
- The Archaeal Cell Cycle.Annual review of cell and developmental biology · 2024Review
- Cell envelope diversity and evolution across the bacterial tree of life.Nature microbiology · 2024Review
- Doxorubicin loaded thermostable nanoarchaeosomes: a next-generation drug carrier for breast cancer therapeutics.Nanoscale advances · 2024Article
- Mode of carbon and energy metabolism shifts lipid composition in the thermoacidophileApplied and environmental microbiology · 2024Article
32 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A vital function of the cell membrane in all living organism is to maintain the membrane permeability barrier and fluidity. The composition of the phospholipid bilayer is distinct in archaea when compared to bacteria and eukarya. In archaea, isoprenoid hydrocarbon side chains are linked via an ether bond to the sn-glycerol-1-phosphate backbone. In bacteria and eukarya on the other hand, fatty acid side chains are linked via an ester bond to the sn-glycerol-3-phosphate backbone. The polar head groups are globally shared in the three domains of life. The unique membrane lipids of archaea have been implicated not only in the survival and adaptation of the organisms to extreme environments but also to form the basis of the membrane composition of the last universal common ancestor (LUCA). In nature, a diverse range of archaeal lipids is found, the most common are the diether (or archaeol) and the tetraether (or caldarchaeol) lipids that form a monolayer. Variations in chain length, cyclization and other modifications lead to diversification of these lipids. The biosynthesis of these lipids is not yet well understood however progress in the last decade has led to a comprehensive understanding of the biosynthesis of archaeol. This review describes the current knowledge of the biosynthetic pathway of archaeal ether lipids; insights on the stability and robustness of archaeal lipid membranes; and evolutionary aspects of the lipid divide and the LUCA. It examines recent advances made in the field of pathway reconstruction in bacteria.
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