Trial reportThe Journal of neuroscience : the official journal of the Society for Neuroscience2014
Dopamine modulates the neural representation of subjective value of food in hungry subjects.
Trial report in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- Economic value in the Brain: A meta-analysis of willingness-to-pay using the Becker-DeGroot-Marschak auction.PloS one · 2023Pooled it
- Neural Correlates of Anti-appetite Medications: An fMRI Meta-analysis.Current neuropharmacology · 2021Pooled it
- Dopamine Modulates Adaptive Prediction Error Coding in the Human Midbrain and Striatum.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Trial
- Dopamine Depletion Reduces Food-Related Reward Activity Independent of BMI.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2016Trial
- Altered neuronal response to visual food stimuli in adolescents undergoing chronic sleep restriction.Sleep · 2024Article
- Single-Dimensional Human Brain Signals for Two-Dimensional Economic Choice Options.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Experimentally revealed stochastic preferences for multicomponent choice options.Journal of experimental psychology. Animal learning and cognition · 2020Article
- Phasic dopamine responses to a food-predictive cue are suppressed by the glucagon-like peptide-1 receptor agonist Exendin-4.Physiology & behavior · 2020Article
- Mesolimbic dopamine D2 receptors and neural representations of subjective value.Scientific reports · 2019Article
- Dopaminergic influences on risk preferences of Parkinson's disease patients.Cognitive, affective & behavioral neuroscience · 2019Article
- Computing Value from Quality and Quantity in Human Decision-Making.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- The Role of Frontostriatal Systems in Instructed Reinforcement Learning: Evidence From Genetic and Experimentally-Induced Variation.Frontiers in human neuroscience · 2018Article
- Cross-talk between the epigenome and neural circuits in drug addiction.Progress in brain research · 2017Review
- Abnormal Frontostriatal Activity During Unexpected Reward Receipt in Depression and Schizophrenia: Relationship to Anhedonia.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2016Article
- Hedonics Act in Unison with the Homeostatic System to Unconsciously Control Body Weight.Frontiers in nutrition · 2016Review
- Endogenous Glucagon-like Peptide-1 Suppresses High-Fat Food Intake by Reducing Synaptic Drive onto Mesolimbic Dopamine Neurons.Cell reports · 2015Article
- Social signals of safety and risk confer utility and have asymmetric effects on observers' choices.Nature neuroscience · 2015Article
- Pleasure systems in the brain.Neuron · 2015Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
Although there is a rich literature on the role of dopamine in value learning, much less is known about its role in using established value estimations to shape decision-making. Here we investigated the effect of dopaminergic modulation on value-based decision-making for food items in fasted healthy human participants. The Becker-deGroot-Marschak auction, which assesses subjective value, was examined in conjunction with pharmacological fMRI using a dopaminergic agonist and an antagonist. We found that dopamine enhanced the neural response to value in the inferior parietal gyrus/intraparietal sulcus, and that this effect predominated toward the end of the valuation process when an action was needed to record the value. Our results suggest that dopamine is involved in acting upon the decision, providing additional insight to the mechanisms underlying impaired decision-making in healthy individuals and clinical populations with reduced dopamine levels.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.