Trial reportThe Journal of neuroscience : the official journal of the Society for Neuroscience2014
Human subthalamic nucleus in movement error detection and its evaluation during visuomotor adaptation.
Trial report in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed.
- Neurofeedback-Linked Suppression of Cortical β Bursts Speeds Up Movement Initiation in Healthy Motor Control: A Double-Blind Sham-Controlled Study.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Trial
- Electrophysiological Signatures of Planned and Unplanned Continuous Movement Termination in Parkinson's Disease.eNeuro · 2025Article
- Article
- Differential Beta and Gamma Activity Modulation during Unimanual and Bimanual Motor Learning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Postmovement Beta Rebound in Real and Imagined Movement.Motor control · 2025Article
- Interdependence patterns of multifrequency oscillations predict visuomotor behavior.Network neuroscience (Cambridge, Mass.) · 2025Article
- Subthalamic control of impulsive actions: insights from deep brain stimulation in Parkinson's disease.Brain : a journal of neurology · 2024Review
- Brain Networks Modulation during Simple and Complex Gait: A "Mobile Brain/Body Imaging" Study.Sensors (Basel, Switzerland) · 2024Article
- Uncovering the neurophysiology of mood, motivation and behavioral symptoms in Parkinson's disease through intracranial recordings.NPJ Parkinson's disease · 2023Review
- Dynamic modulation of subthalamic nucleus activity facilitates adaptive behavior.PLoS biology · 2023Article
- Frontal increase of beta modulation during the practice of a motor task is enhanced by visuomotor learning.Scientific reports · 2021Article
- Phase of firing coding of learning variables across the fronto-striatal network during feature-based learning.Nature communications · 2020Article
- Rapid motor fluctuations reveal short-timescale neurophysiological biomarkers of Parkinson's disease.Journal of neural engineering · 2020Article
- Debugging Adaptive Deep Brain Stimulation for Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2020Review
- Article
- A Case-Controlled Pilot Study on Rhythmic Auditory Stimulation-Assisted Gait Training and Conventional Physiotherapy in Patients With Parkinson's Disease Submitted to Deep Brain Stimulation.Frontiers in neurology · 2020Article
- Brain Activity Reveals Multiple Motor-Learning Mechanisms in a Real-World Task.Frontiers in human neuroscience · 2020Article
- Prior Practice Affects Movement-Related Beta Modulation and Quiet Wake Restores It to Baseline.Frontiers in systems neuroscience · 2020Article
- Beta synchrony in the cortico-basal ganglia network during regulation of force control on and off dopamine.Neurobiology of disease · 2019Article
- Cognitive control involves theta power within trials and beta power across trials in the prefrontal-subthalamic network.Brain : a journal of neurology · 2018Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Monitoring and evaluating movement errors to guide subsequent movements is a critical feature of normal motor control. Previously, we showed that the postmovement increase in electroencephalographic (EEG) beta power over the sensorimotor cortex reflects neural processes that evaluate motor errors consistent with Bayesian inference (Tan et al., 2014). Whether such neural processes are limited to this cortical region or involve the basal ganglia is unclear. Here, we recorded EEG over the cortex and local field potential (LFP) activity in the subthalamic nucleus (STN) from electrodes implanted in patients with Parkinson's disease, while they moved a joystick-controlled cursor to visual targets displayed on a computer screen. After movement offsets, we found increased beta activity in both local STN LFP and sensorimotor cortical EEG and in the coupling between the two, which was affected by both error magnitude and its contextual saliency. The postmovement increase in the coupling between STN and cortex was dominated by information flow from sensorimotor cortex to STN. However, an information drive appeared from STN to sensorimotor cortex in the first phase of the adaptation, when a constant rotation was applied between joystick inputs and cursor outputs. The strength of the STN to cortex drive correlated with the degree of adaption achieved across subjects. These results suggest that oscillatory activity in the beta band may dynamically couple the sensorimotor cortex and basal ganglia after movements. In particular, beta activity driven from the STN to cortex indicates task-relevant movement errors, information that may be important in modifying subsequent motor responses.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.