Evidence map›Paper›PMID 25505221›Full record

Trial reportNeurorehabilitation and neural repair2015

Strategy Training Shows Promise for Addressing Disability in the First 6 Months After Stroke.

Elizabeth R Skidmore, Deirdre R Dawson, Meryl A Butters, Emily S Grattan, Shannon B Juengst, Ellen M Whyte, Amy Begley, Margo B Holm, James T Becker

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Neurorehabilitation and neural repair, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05248178 (Pilot Testing of tDCS and Metacognitive Strategy Training in Chronic Stroke), which is not on this map. Cited by 34 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 4 pooled it
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05248178 naterminatednot on this mapstarted 2022, after this paper: background citation

Pilot Testing of tDCS and Metacognitive Strategy Training in Chronic Stroke

TypeinterventionalSponsorUniversity of Missouri-ColumbiaRan2022 to 2025Enrolled11ConditionsChronic StrokeArmsCO-OP Procedures, tDCS, Computer Cognitive Training Procedures, sham tDCS group
3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 4 syntheses or guidelines pooled it, 83 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Occupational therapy for cognitive impairment in stroke patients.The Cochrane database of systematic reviews · 2022
    Pooled it
  4. Cognitive rehabilitation for attention deficits following stroke.The Cochrane database of systematic reviews · 2019
    Pooled it
  5. Trial
  6. Trial
  7. Trial
  8. Lesion location may attenuate response to strategy training in acute stroke.PM & R : the journal of injury, function, and rehabilitation · 2022
    Trial
  9. Trial
  10. Trial
  11. Strategy Training During Inpatient Rehabilitation May Prevent Apathy Symptoms After Acute Stroke.PM & R : the journal of injury, function, and rehabilitation · 2015
    Trial
  12. Self-Awareness and Recovery of Independence With Strategy Training.The American journal of occupational therapy : official publication of the American Occupational Therapy Association
    Trial
  13. Combined Cognitive-Strategy and Task-Specific Training Affects Cognition and Upper-Extremity Function in Subacute Stroke: An Exploratory Randomized Controlled Trial.The American journal of occupational therapy : official publication of the American Occupational Therapy Association
    Trial
  14. Comparing the CO-OP ApproachBrain sciences · 2025
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Elizabeth R SkidmoreUniversity of Pittsburgh, Pittsburgh, PA, USA skidmore@pitt.edu.
Deirdre R DawsonRotman Research Institute at Baycrest, Toronto, Ontario, Canada University of Toronto, Toronto, Ontario, Canada.
Meryl A ButtersUniversity of Pittsburgh, Pittsburgh, PA, USA Western Psychiatric Institute & Clinic, Pittsburgh, PA, USA.
Emily S GrattanUniversity of Pittsburgh, Pittsburgh, PA, USA.
Shannon B JuengstUniversity of Pittsburgh, Pittsburgh, PA, USA.
Ellen M WhyteUniversity of Pittsburgh, Pittsburgh, PA, USA Western Psychiatric Institute & Clinic, Pittsburgh, PA, USA.
Amy BegleyUniversity of Pittsburgh, Pittsburgh, PA, USA Western Psychiatric Institute & Clinic, Pittsburgh, PA, USA.
Margo B HolmUniversity of Pittsburgh, Pittsburgh, PA, USA.
James T BeckerUniversity of Pittsburgh, Pittsburgh, PA, USA.
University of Pittsburgh · USBaycrest Hospital · CA

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR000005 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2012 to 2015
$50.8M
MULTICENTER CAREER DEVELOPMENT PROGRAM FOR PHYSICAL AND OCCUPATIONAL THERAPYK12HD055931 · NICHD · WASHINGTON UNIVERSITY · PI HAYES, MARCIE HARRIS · 2007 to 2021
$12.7M
RESEARCH METHODS COREP30MH090333 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DEW, MARY AMANDA · 2011 to 2015
$8.3M
Closing Gap in Stroke Rehabilitation: Early Intervention for Cognitive DisabilityR01HD074693 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SKIDMORE, ELIZABETH RENEE · 2013 to 2018
$2.6M
NCATS NIH HHS UL1 TR000005NICHD NIH HHS K12 HD055931NICHD NIH HHS R01 HD074693NIMH NIH HHS P30 MH090333
6 · The paper itself

Abstract

backgroundCognitive impairments occur frequently after stroke and contribute to significant disability. Strategy training shows promise but has not been examined in the acute phase of recovery.

objectiveWe conducted a single-blind randomized pilot study estimating the effect of strategy training, relative to reflective listening (attention control), for reducing disability and executive cognitive impairments.

methodsThirty participants with acute stroke who were enrolled in inpatient rehabilitation and had cognitive impairments were randomized to receive strategy training (n = 15, 10 sessions as adjunct to usual inpatient rehabilitation) or reflective listening (n = 15, same dose). The Functional Independence Measure assessed disability at baseline, rehabilitation discharge, 3, and 6 months. The Color Word Interference Test of the Delis-Kaplan Executive Function System assessed selected executive cognitive impairments (inhibition, flexibility) at baseline, 3, and 6 months.

resultsChanges in Functional Independence Measure scores for the 2 groups over 6 months showed significant effects of group (F1,27 = 9.25, P = .005), time (F3,74 = 96.00, P < .001), and group * time interactions (F3,74 = 4.37, P < .007) after controlling for baseline differences in stroke severity (F1,27 = 6.74, P = .015). Color Word Interference Inhibition scores showed significant effects of group (F1,26 = 6.50, P = .017) and time (F2,34 = 4.74, P = .015), but the group * time interaction was not significant (F2,34 = 2.55, P = .093). Color Word Interference Cognitive Flexibility scores showed significant effects of group (F1,26 = 23.41, P < .001), time (F2,34 = 12.77, P < .001), and group * time interactions (F2,34 = 7.83, P < .002). Interaction effects suggested greater improvements were associated with strategy training.

conclusionsStrategy training shows promise for addressing disability in the first 6 months after stroke. Lessons from this pilot study may inform future clinical trials.

Indexed as

Physical Therapy ModalitiesStroke RehabilitationActivities of Daily LivingBehavior TherapyCognition DisordersDisability EvaluationExecutive FunctionFemaleHumansMaleNeuropsychological TestsSingle-Blind MethodStrokecognitioninterventionrehabilitationstrategy trainingstroke

Identifiers

PMID25505221
PMCPMC4465421
OpenAlexW2047825905

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.