ArticleJournal of applied physiology (Bethesda, Md. : 1985)2015
Aging impairs heat loss, but when does it matter?
Article in Journal of applied physiology (Bethesda, Md. : 1985), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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Who cites it
43 citing papers in PubMed, 113 citations in OpenAlex.
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- Seven days of warm-water immersion enhances resting irisin and BDNF, but not klotho, in older men.Experimental physiology · 2026Article
- Defining Sex- and Age-Specific Initial Stay Times for Continuous Moderate-Intensity Work in Hot Environments Before Heat-Mitigation Controls Are Implemented - Part A.American journal of industrial medicine · 2025Article
- Defining Sex- and Age-Specific Initial Stay Times for Continuous Heavy-Intensity Work in Hot Environments Before Heat-Mitigation Controls Are Implemented-Part B.American journal of industrial medicine · 2025Article
- Real-time measurement of entropy production and export in humans: A step toward entropically informed medicine.Annals of the New York Academy of Sciences · 2025Article
- Effects of 24-h sleep deprivation on whole-body heat exchange in young men during exercise in the heat.European journal of applied physiology · 2025Article
- Experimental research in environmentally induced hyperthermic older persons: A systematic quantitative literature review mapping the available evidence.Temperature (Austin, Tex.) · 2024Article
- Indoor overheating: A review of vulnerabilities, causes, and strategies to prevent adverse human health outcomes during extreme heat events.Temperature (Austin, Tex.) · 2024Review
- A physiological approach for assessing human survivability and liveability to heat in a changing climate.Nature communications · 2023Article
- Serum klotho concentrations in older men with hypertension or type 2 diabetes during prolonged exercise in temperate and hot conditions.European journal of applied physiology · 2023Article
- Energy metabolism and thermoregulation during sleep in young and old females.Scientific reports · 2023Article
- Sensitivity and specificity of using exercise heart rate in a thermoneutral environment to predict heat tolerance status.International journal of occupational medicine and environmental health · 2023Article
- A Systematic Review of Post-Work Core Temperature Cooling Rates Conferred by Passive Rest.Biology · 2023Review
- The effect of age and mitigation strategies during hot water immersion on orthostatic intolerance and thermal stress.Experimental physiology · 2023Article
- Can exposure to heat attenuate neurodegeneration in older adults with Parkinson's disease?Frontiers in aging neuroscience · 2023Article
- Heat-Related Illness in Emergency and Critical Care: Recommendations for Recognition and Management with Medico-Legal Considerations.Biomedicines · 2022Review
- Human temperature regulation under heat stress in health, disease, and injury.Physiological reviews · 2022Review
- Heat Strain Evaluation of Power Grid Outdoor Workers Based on a Human Bioheat Model.International journal of environmental research and public health · 2022Article
- Occupational heat strain in outdoor workers: A comprehensive review and meta-analysis.Temperature (Austin, Tex.) · 2022Review
- Impact of uncomplicated controlled hypertension on thermoregulation during exercise-heat stress.Journal of human hypertension · 2021Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aging is associated with an attenuated physiological ability to dissipate heat. However, it remains unclear if age-related impairments in heat dissipation only occur above a certain level of heat stress and whether this response is altered by aerobic fitness. Therefore, we examined changes in whole body evaporative heat loss (HE) as determined using whole body direct calorimetry in young (n = 10; 21 ± 1 yr), untrained middle-aged (n = 10; 48 ± 5 yr), and older (n = 10; 65 ± 3 yr) males matched for body surface area. We also studied a group of trained middle-aged males (n = 10; 49 ± 5 yr) matched for body surface area with all groups and for aerobic fitness with the young group. Participants performed intermittent aerobic exercise (30-min exercise bouts separated by 15-min rest) in the heat (40°C and 15% relative humidity) at progressively greater fixed rates of heat production equal to 300 (Ex1), 400 (Ex2), and 500 (Ex3) W. Results showed that HE was significantly lower in middle-aged untrained (Ex2: 426 ± 34; and Ex3: 497 ± 17 W) and older (Ex2: 424 ± 38; and Ex3: 485 ± 44 W) compared with young (Ex2: 472 ± 42; and Ex3: 558 ± 51 W) and middle-aged trained (474 ± 21; Ex3: 552 ± 23 W) males at the end of Ex2 and Ex3 (P < 0.05). No differences among groups were observed during recovery. We conclude that impairments in HE in older and middle-aged untrained males occur at exercise-induced heat loads of ≥400 W when performed in a hot environment. These impairments in untrained middle-aged males can be minimized through regular aerobic exercise training.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.