ArticleTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik2015
The sh2-R allele of the maize shrunken-2 locus was caused by a complex chromosomal rearrangement.
Article in TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 32 citations in OpenAlex.
- Integrated transcriptomic and metabolomic analysis of a mutant reveals the potential mechanism of endosperm content increase in sweet-waxy double recessive maize.BMC plant biology · 2026Article
- A simple method to efficiently generate structural variation in plants.PLoS genetics · 2025Article
- Enrichment of phytoglycogen in sweet corn kernels through genomics-assisted selection.Functional & integrative genomics · 2025Article
- Multi-layer molecular analysis reveals distinctive metabolomic and transcriptomic profiles of different sweet corn varieties.Frontiers in plant science · 2024Article
- Review
- Profiling and Quantification of Anthocyanins in Purple-Pericarp Sweetcorn and Purple-Pericarp Maize.Molecules (Basel, Switzerland) · 2023Article
- Article
- Breaking the tight genetic linkage between the a1 and sh2 genes led to the development of anthocyanin-rich purple-pericarp super-sweetcorn.Scientific reports · 2023Article
- Genetic basis of the oil biosynthesis in ultra-high-oil maize grains with an oil content exceeding 20.Frontiers in plant science · 2023Article
- Identification of Genetic Variations and Candidate Genes Responsible for Stalk Sugar Content and Agronomic Traits in Fresh Corn via GWAS across Multiple Environments.International journal of molecular sciences · 2022Article
- Article
- Transcriptome-wide association and prediction for carotenoids and tocochromanols in fresh sweet corn kernels.The plant genome · 2022Article
- Allelic variation in shrunken2 gene affecting kernel sweetness in exotic-and indigenous-maize inbreds.PloS one · 2022Article
- Genome assembly and population genomic analysis provide insights into the evolution of modern sweet corn.Nature communications · 2021Article
- The dynamic transcriptome of waxy maize (Zea mays L. sinensis Kulesh) during seed development.Genes & genomics · 2020Article
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Authors and funding
4 authors at 3 institutions in 3 countries.
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No grant is acknowledged in the PubMed record.
Abstract
key messageThe mutant that originally defined the shrunken - 2 locus of maize is shown here to be the product of a complex chromosomal rearrangement. The maize shrunken-2 gene (sh2) encodes the large subunit of the heterotetrameric enzyme, adenosine diphosphate glucose pyrophosphorylases and a rate-limiting enzyme in starch biosynthesis. The sh2 gene was defined approximately 72 years ago by the isolation of a loss-of-function allele conditioning a shrunken, but viable seed. In subsequent years, the realization that this allele, termed zsh2-R or sh2-Reference, causes an extremely high level of sucrose to accumulate in the developing seed led to a revolution in the sweet corn industry. Now, the vast majority of sweet corns grown throughout the world contain this mutant allele. Through initial Southern analysis followed by genomic sequencing, the work reported here shows that this allele arose through a complex set of events involving at least three breaks of chromosome 3 as well as an intra-chromosomal inversion. These findings provide an explanation for some previously reported, unexpected observations concerning rates of recombination within and between genes in this region.
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