Evidence map›Paper›PMID 25504416›Full record

ArticleAdvanced materials (Deerfield Beach, Fla.)2015

An imagable and photothermal "Abraxane-like" nanodrug for combination cancer therapy to treat subcutaneous and metastatic breast tumors.

Qian Chen, Chao Liang, Chao Wang, Zhuang Liu

Abstract read
PubMed Publisher
In one paragraph

Article in Advanced materials (Deerfield Beach, Fla.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 107 papers.

0numbers the graph read from it
0cells of the map it votes in
107citing papers in PubMed
20.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

107 citing papers in PubMed, 444 citations in OpenAlex.

  1. Article
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  4. Laser fragmentation of MoSBeilstein journal of nanotechnology · 2026
    Article
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  15. "Abraxane-Like" Radiosensitizer for In Situ Oral Cancer Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  16. Review
  17. Review
  18. Review
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  20. Article

47 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Qian ChenInstitute of Functional Nano & Soft Materials (FUNSOM), Collaborative Innovation Center of Suzhou Nano Science & Technology, Soochow University, Suzhou, Jiangsu, 215123, China.
Chao Liang
Chao Wang
Zhuang Liu
Soochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A new "Abraxane-like" nanotheranostic formulation self-assembled from three clinically approved agents, human serum albumin, paclitaxel, and indocyanine green, is developed. Utilizing such a newly formulated nanodrug, combined photothermal and chemotherapy is conducted under the guidance of imaging, not only effectively eliminating subcutaneous tumors, but also significantly inhibiting the development of metastatic tumors in this proof-of-concept study.

Indexed as

Albumin-Bound PaclitaxelAlbuminsBreast NeoplasmsCell Line, TumorChemistry, PharmaceuticalDrug Therapy, CombinationFemaleHumansIndocyanine GreenModels, MolecularNanoparticlesNeoplasm MetastasisPaclitaxelPhototherapyProtein ConformationSubcutaneous TissueAlbumin-Bound PaclitaxelAlbuminsIndocyanine GreenPaclitaxelcombination therapyhuman serum albuminindocyanine greenlung metastasispaclitaxel

Identifiers

PMID25504416
OpenAlexW2083350623

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.