ArticleNature communications2014
Response-dependent dynamics of cell-specific inhibition in cortical networks in vivo.
Article in Nature communications, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
37 citing papers in PubMed, 65 citations in OpenAlex.
- Context-dependent activation of V1 parvalbumin interneurons enhances visual discrimination.PLoS biology · 2025Article
- Characterizing optogenetically mediated rebound effects in anaesthetized mouse primary visual cortex.The Journal of physiology · 2025Article
- Filter-based models of suppression in retinal ganglion cells: Comparison and generalization across species and stimuli.PLoS computational biology · 2025Article
- Lateral inhibition in V1 controls neural and perceptual contrast sensitivity.Nature neuroscience · 2025Article
- Simultaneous interneuron labeling reveals cell type-specific, population-level interactions in cortex.iScience · 2024Article
- Simultaneous interneuron labeling reveals population-level interactions among parvalbumin, somatostatin, and pyramidal neurons in cortex.bioRxiv : the preprint server for biology · 2024Article
- Dynamic Distortion of Orientation Representation after Learning in the Mouse Primary Visual Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Constrained brain volume in an efficient coding model explains the fraction of excitatory and inhibitory neurons in sensory cortices.PLoS computational biology · 2022Article
- Parvalbumin-Positive Interneurons Regulate Cortical Sensory Plasticity in Adulthood and Development Through Shared Mechanisms.Frontiers in neural circuits · 2022Review
- Comprehensive characterization of oscillatory signatures in a model circuit with PV- and SOM-expressing interneurons.Biological cybernetics · 2021Article
- Neocortical inhibitory interneuron subtypes are differentially attuned to synchrony- and rate-coded information.Communications biology · 2021Article
- Inhibitory stabilization and cortical computation.Nature reviews. Neuroscience · 2021Review
- Dopamine Differentially Regulates Response Dynamics of Prefrontal Cortical Principal Neurons and Interneurons to Optogenetic Stimulation of Inputs from Ventral Tegmental Area.Cerebral cortex (New York, N.Y. : 1991) · 2020Article
- Patterned perturbation of inhibition can reveal the dynamical structure of neural processing.eLife · 2020Article
- Mechanisms underlying gain modulation in the cortex.Nature reviews. Neuroscience · 2020Review
- Mapping Brain-Wide Afferent Inputs of Parvalbumin-Expressing GABAergic Neurons in Barrel Cortex Reveals Local and Long-Range Circuit Motifs.Cell reports · 2019Article
- Amplifying the redistribution of somato-dendritic inhibition by the interplay of three interneuron types.PLoS computational biology · 2019Article
- Gradient of Parvalbumin- and Somatostatin-Expressing Interneurons Across Cingulate Cortex Is Differentially Linked to Aggression and Sociability in BALB/cJ Mice.Frontiers in psychiatry · 2019Article
- Divisive Inhibition Prevails During Simultaneous Optogenetic Activation of All Interneuron Subtypes in Mouse Primary Visual Cortex.Frontiers in neural circuits · 2019Article
- GABA, not BOLD, reveals dissociable learning-dependent plasticity mechanisms in the human brain.eLife · 2018Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
In the visual cortex, inhibitory neurons alter the computations performed by target cells via combination of two fundamental operations, division and subtraction. The origins of these operations have been variously ascribed to differences in neuron classes, synapse location or receptor conductances. Here, by utilizing specific visual stimuli and single optogenetic probe pulses, we show that the function of parvalbumin-expressing and somatostatin-expressing neurons in mice in vivo is governed by the overlap of response timing between these neurons and their targets. In particular, somatostatin-expressing neurons respond at longer latencies to small visual stimuli compared with their target neurons and provide subtractive inhibition. With large visual stimuli, however, they respond at short latencies coincident with their target cells and switch to provide divisive inhibition. These results indicate that inhibition mediated by these neurons is a dynamic property of cortical circuits rather than an immutable property of neuronal classes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.