SynthesisScientific reports2014
Body mass index and risk of breast cancer: a nonlinear dose-response meta-analysis of prospective studies.
Synthesis in Scientific reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 4 syntheses or guidelines pooled it, 88 citations in OpenAlex.
- Pooled it
- Body mass index had different effects on premenopausal and postmenopausal breast cancer risks: a dose-response meta-analysis with 3,318,796 subjects from 31 cohort studies.BMC public health · 2017Pooled it
- Abdominal obesity and gastroesophageal cancer risk: systematic review and meta-analysis of prospective studies.Bioscience reports · 2017Pooled it
- Abdominal Obesity and Lung Cancer Risk: Systematic Review and Meta-Analysis of Prospective Studies.Nutrients · 2016Pooled it
- Association of lifestyle factors with breast cancer incidence: An overview of systematic reviews.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2025Article
- Abdominal obesity and paraspinal muscles in computed tomography image: relationships with triple negative breast cancer.American journal of cancer research · 2025Article
- Evaluation of a mobile behavior change program for weight loss in breast cancer survivors.NPJ breast cancer · 2024Article
- Review
- Trends in the burden of most common obesity-related cancers in 16 Southern Africa development community countries, 1990-2019. Findings from the global burden of disease study.Obesity science & practice · 2024Article
- Mediation effects of metabolites and sex hormones on the relationship between body mass index and breast cancer: Mendelian randomization analysis and mediation analysis.Frontiers in oncology · 2024Article
- Mesalazine Inhibits Amyloid Formation and Destabilizes Pre-formed Amyloid Fibrils in the Human Insulin.Journal of fluorescence · 2023Article
- Management of obesity across women's life course: FIGO Best Practice Advice.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2023Article
- The role of obesity and bariatric surgery-induced weight loss in breast cancer.Cancer metastasis reviews · 2022Review
- Body mass index, breast density, and the risk of breast cancer development in relation to the menopausal status; results from a population-based screening program in a native African-Arab country.Acta radiologica open · 2022Article
- Examining the impacts of neighborhood poverty on bodyweight across the BMI distribution: a quantile and MSM modeling approach.Annals of epidemiology · 2021Article
- Gender Differences in Obesity-Related Cancers.Current obesity reports · 2021Review
- A prospective study of type 2 diabetes, metformin use, and risk of breast cancer.Annals of oncology : official journal of the European Society for Medical Oncology · 2021Article
- Associations of Biomarkers of Inflammation and Breast Cancer in the Breast Adipose Tissue of Women with Combined Measures of Adiposity.Journal of obesity · 2021Article
- Geographic Inequalities in Breast Cancer in Italy: Trend Analysis of Mortality and Risk Factors.International journal of environmental research and public health · 2020Article
- Dietary fat and obesity as modulators of breast cancer risk: Focus on DNA methylation.British journal of pharmacology · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The role of Body Mass Index (BMI) for Breast Cancer (BC) remains to be great interest for a long time. However, the precise effect of nonlinear dose-response for BMI and BC risk is still unclear. We conducted a dose-response meta-analysis to quantitatively assess the effect of BMI on BC risk. Twelve prospective studies with 4,699 cases identified among 426,199 participants and 25 studies of 22,809 cases identified among 1,155,110 participants in premenopausal and postmenopausal groups, respectively, were included in this meta-analysis. Significant non-linear dose-response (P < 0.001) association was identified between BMI and BC risk in postmenopausal women. Individuals with BMI of 25, 30, and 35 kg/m(2) yielded relative risks (RRs) of 1.02 [95% confidence interval (CI): 0.98-1.06], 1.12 (95% CI: 1.01-1.24), and 1.26 (95% CI: 1.07-1.50), respectively, when compared to the mean level of the normal BMI range. However, inverse result though not significant was observed in premenopausal women. In conclusion, the results of this meta-analysis highlighted that obesity contributed to increased BC risk in a nonlinear dose-response manner in postmenopausal women, and it is important to realize that body weight control may be a crucial process to reduce BC susceptibility.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.