Evidence map›Paper›PMID 25503954›Full record

ArticleClinical kidney journal2014

Malignant hypertension with thrombotic microangiopathy and persistent acute kidney injury (AKI).

Chike Nzerue, Kemi Oluwole, David Adejorin, Paisit Paueksakon, Richard Fremont, Richmond Akatue, Marquetta Faulkner

Abstract read
In one paragraph

Article in Clinical kidney journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chike NzerueDepartment of Medicine, Meharry Medical College, Nashville, TN, USA ; Section of Renal Diseases,Vanderbilt University School of Medicine, Nashville, TN, USA.
Kemi OluwoleDepartment of Medicine, Meharry Medical College, Nashville, TN, USA.
David AdejorinDepartment of Medicine, Meharry Medical College, Nashville, TN, USA.
Paisit PaueksakonRenal Pathology division, Vanderbilt University School of Medicine, Nashville, TN, USA.
Richard FremontDepartment of Medicine, Meharry Medical College, Nashville, TN, USA ; Division of Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA.
Richmond AkatueDepartment of Medicine, Meharry Medical College, Nashville, TN, USA.
Marquetta FaulknerDepartment of Medicine, Meharry Medical College, Nashville, TN, USA ; Section of Renal Diseases,Vanderbilt University School of Medicine, Nashville, TN, USA.

Funding

Meharry RCMI Program in Women's Health ResearchG12MD007586 · NIMHD · MEHARRY MEDICAL COLLEGE · PI HILDRETH, JAMES E · 2012 to 2016
$7.8M
NIMHD NIH HHS G12 MD007586
6 · The paper itself

Abstract

Two cases of malignant hypertension presenting with acute kidney injury, thrombocytopenia and hemolytic anemia are presented. In both patients a prolonged duration of renal replacement therapy was required. The plasma levels of ADAMTS13 enzyme were not helpful in delineating the precise pathogenesis in both cases, as the decrements were not severe. We discuss the clinic-pathologic correlation of the biopsy findings and persistence of AKI.

Indexed as

irreversiblemalignant hypertensionthrombotic microangiopathy

Identifiers

PMID25503954
PMCPMC4240409

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.