ArticleThe Journal of comparative neurology2015
Feedback in the brainstem: an excitatory disynaptic pathway for control of whisking.
Article in The Journal of comparative neurology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 26 citations in OpenAlex.
- The cerebellum engages multiple pre-motor pathways through a divergent-convergent architecture to shape whisker dynamics.Frontiers in neural circuits · 2025Article
- A brainstem circuit for the expression of defensive facial reactions in rat.Current biology : CB · 2023Article
- Neurocircuitry underlying the antidepressant effect of retrograde facial botulinum toxin in mice.Cell & bioscience · 2023Article
- Orofacial Movements Involve Parallel Corticobulbar Projections from Motor Cortex to Trigeminal Premotor Nuclei.Neuron · 2019Article
- Circuits in the rodent brainstem that control whisking in concert with other orofacial motor actions.Neuroscience · 2018Review
- Parallel Inhibitory and Excitatory Trigemino-Facial Feedback Circuitry for Reflexive Vibrissa Movement.Neuron · 2017Article
- Immunocytochemical organization and sour taste activation in the rostral nucleus of the solitary tract of mice.The Journal of comparative neurology · 2017Article
- Somatotopy in the Medullary Dorsal Horn As a Basis for Orofacial Reflex Behavior.Frontiers in neurology · 2017Article
- Article
- Corticofugal projection patterns of whisker sensorimotor cortex to the sensory trigeminal nuclei.Frontiers in neural circuits · 2015Article
- Vibrissa Self-Motion and Touch Are Reliably Encoded along the Same Somatosensory Pathway from Brainstem through Thalamus.PLoS biology · 2015Article
- The Brainstem Oscillator for Whisking and the Case for Breathing as the Master Clock for Orofacial Motor Actions.Cold Spring Harbor symposia on quantitative biology · 2014Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
Abstract
Sensorimotor processing relies on hierarchical neuronal circuits to mediate sensory-driven behaviors. In the mouse vibrissa system, trigeminal brainstem circuits are thought to mediate the first stage of vibrissa scanning control via sensory feedback that provides reflexive protraction in response to stimulation. However, these circuits are not well defined. Here we describe a complete disynaptic sensory receptor-to-muscle circuit for positive feedback in vibrissa movement. We identified a novel region of trigeminal brainstem, spinal trigeminal nucleus pars muralis, which contains a class of vGluT2+ excitatory projection neurons involved in vibrissa motor control. Complementary single- and dual-labeling with traditional and virus tracers demonstrate that these neurons both receive primary inputs from vibrissa sensory afferent fibers and send monosynaptic connections to facial nucleus motoneurons that directly innervate vibrissa musculature. These anatomical results suggest a general role of disynaptic architecture in fast positive feedback for motor output that drives active sensation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.