ArticlePLoS computational biology2014
Oscillation-induced signal transmission and gating in neural circuits.
Article in PLoS computational biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Neurodynamical Computing at the Information Boundaries of Intelligent Systems.Cognitive computation · 2024Article
- Inter-areal transmission of multiple neural signals through frequency-division-multiplexing communication.Cognitive neurodynamics · 2023Article
- High-frequency oscillations and sequence generation in two-population models of hippocampal region CA1.PLoS computational biology · 2022Article
- Translational neuronal ensembles: Neuronal microcircuits in psychology, physiology, pharmacology and pathology.Frontiers in systems neuroscience · 2022Review
- Article
- Fluctuation-induced distributed resonances in oscillatory networks.Science advances · 2019Article
- Graded, Dynamically Routable Information Processing with Synfire-Gated Synfire Chains.PLoS computational biology · 2016Article
- Dynamic effective connectivity in cortically embedded systems of recurrently coupled synfire chains.Journal of computational neuroscience · 2016Article
- Effects of Calcium Spikes in the Layer 5 Pyramidal Neuron on Coincidence Detection and Activity Propagation.Frontiers in computational neuroscience · 2016Article
- A Unified Dynamic Model for Learning, Replay, and Sharp-Wave/Ripples.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- Neural Sequence Generation Using Spatiotemporal Patterns of Inhibition.PLoS computational biology · 2015Article
- Hippocampal sharp wave-ripple: A cognitive biomarker for episodic memory and planning.Hippocampus · 2015Review
- A mechanism for graded, dynamically routable current propagation in pulse-gated synfire chains and implications for information coding.Journal of computational neuroscience · 2015Article
- When less is more: non-monotonic spike sequence processing in neurons.PLoS computational biology · 2015Article
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Authors and funding
3 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Reliable signal transmission constitutes a key requirement for neural circuit function. The propagation of synchronous pulse packets through recurrent circuits is hypothesized to be one robust form of signal transmission and has been extensively studied in computational and theoretical works. Yet, although external or internally generated oscillations are ubiquitous across neural systems, their influence on such signal propagation is unclear. Here we systematically investigate the impact of oscillations on propagating synchrony. We find that for standard, additive couplings and a net excitatory effect of oscillations, robust propagation of synchrony is enabled in less prominent feed-forward structures than in systems without oscillations. In the presence of non-additive coupling (as mediated by fast dendritic spikes), even balanced oscillatory inputs may enable robust propagation. Here, emerging resonances create complex locking patterns between oscillations and spike synchrony. Interestingly, these resonances make the circuits capable of selecting specific pathways for signal transmission. Oscillations may thus promote reliable transmission and, in co-action with dendritic nonlinearities, provide a mechanism for information processing by selectively gating and routing of signals. Our results are of particular interest for the interpretation of sharp wave/ripple complexes in the hippocampus, where previously learned spike patterns are replayed in conjunction with global high-frequency oscillations. We suggest that the oscillations may serve to stabilize the replay.
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