Trial reportInternational urology and nephrology2015
Impact of home-based aerobic exercise on the physical capacity of overweight patients with chronic kidney disease.
Trial report in International urology and nephrology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 17 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 17 syntheses or guidelines pooled it, 78 citations in OpenAlex.
- Pooled it
- Pooled it
- The effect of exercise training in people with pre-dialysis chronic kidney disease: a systematic review with meta-analysis.Journal of nephrology · 2024Pooled it
- Effects of additional physical exercise on the nutritional status and disease progression during the low-protein diet in Chronic Kidney Disease Patients: a systematic review and meta-analysis.European journal of clinical nutrition · 2024Pooled it
- Effect of exercise interventions for sleep quality in patients with chronic kidney disease: a systematic review and meta-analysis.International urology and nephrology · 2023Pooled it
- Effects of exercise on markers of inflammation and indicators of nutrition in patients with chronic kidney disease: a systematic review and meta-analysis.International urology and nephrology · 2022Pooled it
- The effect of regular aerobic exercise on renal function in patients with CKD: A systematic review and meta-analysis.Frontiers in physiology · 2022Pooled it
- Interventions for weight loss in people with chronic kidney disease who are overweight or obese.The Cochrane database of systematic reviews · 2021Pooled it
- Efficacy of aerobic exercise on the cardiometabolic and renal outcomes in patients with chronic kidney disease: a systematic review of randomized controlled trials.Journal of nephrology · 2021Pooled it
- Effects of exercise on kidney and physical function in patients with non-dialysis chronic kidney disease: a systematic review and meta-analysis.Scientific reports · 2020Pooled it
- Exercise therapy improves eGFR, and reduces blood pressure and BMI in non-dialysis CKD patients: evidence from a meta-analysis.BMC nephrology · 2019Pooled it
- Lifestyle behaviour change for preventing the progression of chronic kidney disease: a systematic review.BMJ open · 2019Pooled it
- Aerobic exercise in adults with chronic kidney disease (CKD): a meta-analysis.International urology and nephrology · 2019Pooled it
- Pooled it
- The impact of exercise on physical function, cardiovascular outcomes and quality of life in chronic kidney disease patients: a systematic review.International urology and nephrology · 2018Pooled it
- Pooled it
- Exercise Affects Cardiopulmonary Function in Patients with Chronic Kidney Disease: A Meta-Analysis.BioMed research international · 2017Pooled it
- Telerehabilitation exercise program in pediatric patients after kidney transplantation: a randomized clinical trial.Pediatric nephrology (Berlin, Germany) · 2026Trial
- The Borg scale is safe and efficacious for prescribing and monitoring self-administered balance and resistance exercise in patients with chronic kidney disease: a post-hoc analysis of RENEXC, a randomized controlled trial.Journal of rehabilitation medicine · 2025Trial
- Randomized crossover clinical trial of coenzyme Q10 and nicotinamide riboside in chronic kidney disease.JCI insight · 2023Trial
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHome-based exercise has been shown to provide benefits in terms of physical capacity in the general population, but has been scarcely investigated in patients with chronic kidney disease (CKD).
aimsTo evaluate the impact of a home-based aerobic training on the cardiopulmonary and functional capacities of overweight non-dialysis-dependent patients with CKD (NDD-CKD).
methodsTwenty-nine sedentary patients (55.1 ± 11.6 years, BMI = 31.2 ± 6.1 kg/m(2), eGFR = 26.9 ± 17.4 mL/min/1.73 m(2)) were randomly assigned to a home-based exercise group (n = 14) or to a control group (n = 15) that remained without performing exercise. Aerobic training was performed three times per week for 12 weeks. A cardiopulmonary exercise test, functional capacity and clinical parameters were evaluated.
resultsA significant increase, ranging from 8.3 to 17 %, was observed in the cardiopulmonary capacity parameters, such as maximal ventilation (p = 0.005), VO2peak (p = 0.049), ventilatory threshold (p = 0.040) and respiratory compensation point (p < 0.001), of the exercise group. A simultaneous improvement in the functional capacity tests [6-min walk test (p < 0.001), time up and go test (p < 0.001), arm curl test (p < 0.001), sit and stand test (p < 0.001), 2-min step test (p < 0.001) and back scratch test (p = 0.042)] was also found in patients who were submitted to the exercise. Exercised patients experienced a decrease in systolic and diastolic blood pressure, average 10.6 % (p < 0.001) and 9.2 % (p = 0.007), respectively, and a trend toward improved renal function (p = 0.1). No change in any parameter was found in the control group during the follow-up.
conclusionThe home-based aerobic exercise program was feasible, safe and effective for the improvement in the cardiopulmonary and functional capacities of overweight NDD-CKD patients.
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