Evidence map›Paper›PMID 25503304›Full record

ArticleJournal of autism and developmental disorders2015

Autism spectrum disorder risk factors and autistic traits in gender dysphoric children.

Doug P VanderLaan, Jonathan H Leef, Hayley Wood, S Kathleen Hughes, Kenneth J Zucker

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of autism and developmental disorders, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 73 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
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  8. Review
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  11. Autism trait prevalence in treatment seeking adolescents and adults attending specialist gender services.European psychiatry : the journal of the Association of European Psychiatrists · 2020
    Article
  12. Article
  13. Article
  14. Autistic Traits in Treatment-Seeking Transgender Adults.Journal of autism and developmental disorders · 2018
    Article
  15. Article
  16. Potentially Reversible Social Deficits Among Transgender Youth.Journal of autism and developmental disorders · 2018
    Article
  17. Article
  18. Autistic Symptoms in Children and Adolescents with Gender Dysphoria.Journal of autism and developmental disorders · 2018
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Doug P VanderLaanGender Identity Service, Child, Youth, and Family Services, Beamish Family Wing, Centre for Addiction and Mental Health, 80 Workman Way, 5th Floor, Toronto, ON, M6J 1H4, Canada, doug.vanderlaan@camh.ca.
Jonathan H Leef
Hayley Wood
S Kathleen Hughes
Kenneth J Zucker
Centre for Addiction and Mental Health · CA

Funding

Canadian Institutes of Health Research
6 · The paper itself

Abstract

Gender dysphoria (GD) and autism spectrum disorder (ASD) are associated. In 49 GD children (40 natal males), we examined ASD risk factors (i.e., birth weight, parental age, sibling sex ratio) in relation to autistic traits. Data were gathered on autistic traits, birth weight, parents' ages at birth, sibling sex ratio, gender nonconformity, age, maternal depression, general behavioral and emotional problems, and IQ. High birth weight was associated with both high gender nonconformity and autistic traits among GD children. Developmental processes associated with high birth weight are, therefore, likely to underlie the GD-ASD link either directly or indirectly. The present study is the first to provide quantitative data bearing on possible mechanisms that lead GD and ASD to co-occur.

Indexed as

Autism Spectrum DisorderChildFemaleGender DysphoriaHumansMaleProdromal SymptomsRisk Factors

Identifiers

PMID25503304
OpenAlexW2025897634

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.