Evidence map›Paper›PMID 25503248›Full record

ArticleSoft matter2015

Structure of the DMPC lipid bilayer ripple phase.

Kiyotaka Akabori, John F Nagle

Open access · greenAbstract read
In one paragraph

Article in Soft matter, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 97 citations in OpenAlex.

  1. Article
  2. Review
  3. Doniach Lattice Gas on Bipartite Lattices in the Mean-Field Approximation.Langmuir : the ACS journal of surfaces and colloids · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Kiyotaka AkaboriDepartment of Physics, Carnegie Mellon University, Pittsburgh, PA. 15213, USA. nagle@cmu.edu.
John F Nagle
Carnegie Mellon University · USUniversity of Pittsburgh · US

Funding

STRUCTURE OF LIPID BILAYERSR01GM044976 · NIGMS · CARNEGIE-MELLON UNIVERSITY · PI NAGLE, JOHN F, TRISTRAM-NAGLE, STEPHANIE · 1990 to 2014
$3.1M
NIGMS NIH HHS DMR-0225180NIGMS NIH HHS GM 44976NIGMS NIH HHS R01 GM044976
6 · The paper itself

Abstract

High resolution structure is presented for the ripple (Pβ') phase of the phospholipid dimyristoylphosphatidylcholine. Low angle X-ray scattering from oriented samples yielded 57 orders, more than twice as many as recorded previously. The determined electron density map has a sawtooth profile similar to the result from lower resolution data, but the features are sharper allowing better estimates for the modulated bilayer profile and the distribution of headgroups along the aqueous interface. Analysis of high resolution wide angle X-ray data shows that the hydrocarbon chains in the longer, major side of the asymmetric sawtooth are packed similarly to the LβF gel phase, with chains in both monolayers coupled and tilted by 18° in the same direction. The absence of Bragg rods that could be associated with the minor side is consistent with disordered chains, as often suggested in the literature. However, the new high resolution bilayer profile strongly suggests that the chains in the two monolayers in the minor side and the curved region are not in registry. This staggered monolayer modulated melting suggests a direction for improving theories of the ripple phase.

Indexed as

Scattering, Small AngleX-Ray DiffractionDimyristoylphosphatidylcholineLipid BilayersDimyristoylphosphatidylcholineLipid Bilayers

Identifiers

PMID25503248
PMCPMC4303532
OpenAlexW2112877862

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.