ArticleNature2014
Catalytic enantioselective synthesis of quaternary carbon stereocentres.
Article in Nature, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 208 papers.
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Who cites it
208 citing papers in PubMed.
- Modular Access to α-Tertiary Amines: Electrochemical Tandem Di-Functionalization of Olefins With Ammonia Surrogates and Amino Acids.Angewandte Chemie (International ed. in English) · 2026Article
- Iron-catalyzed para-selective alkylation of aryl amides with tertiary Grignard reagents.Molecular diversity · 2026Article
- Chiral 3-acyl-2-pyrrolines as strategic hubs toward polycyclic pyrrolidinesChemical science · 2026Article
- Copper-catalyzed enantioselective allylation of cyclic anhydrides for generation of multiple chiral centers.Nature communications · 2026Article
- Transient Boryl Assistance Enables Stereoselective Alkylation of Acyclic Tetrasubstituted Enolates.Angewandte Chemie (International ed. in English) · 2026Article
- Directed evolution of an enantiocomplementary SNature communications · 2026Article
- Highly Cα-regio-, enantio- and diastereoselective Mukaiyama-type annulation of siloxyfurans: stereodivergent synthesis of multi-stereogenic tricyclic γ-lactones.Chemical science · 2026Article
- Deaminative C(Journal of the American Chemical Society · 2026Article
- Stereospecific Synthesis of Quaternary Stereocenters from Tertiary Benzylic Carboxylates.Organic letters · 2026Article
- Seven-Step Total Synthesis of Conidiogenone B Enabled by Radical Cyclizations.Journal of the American Chemical Society · 2026Article
- Desymmetrization of Malonic Monoesters and Malonic Acids via Enantioselective Catalytic C(spAngewandte Chemie (International ed. in English) · 2026Article
- Tetrachloromethane as an editable all-carbon quaternary source.Nature communications · 2026Article
- Catalytic Enantioselective Cross-Nucleophile Coupling via Valence Tautomerism.Journal of the American Chemical Society · 2025Article
- Organocatalytic Enantioselective Addition of 3-Aryloxindoles to Ethenesulfonyl Fluoride.Organic letters · 2025Article
- Deracemization by coupling electrochemically assisted racemization and asymmetric crystallization.Chemical communications (Cambridge, England) · 2025Article
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- Iron/phosphine-catalyzed reductive cross-coupling to construct quaternary carbon centers.Nature communications · 2025Article
- Stereoselective Photoenzymatic Hydroarylation for the Construction of Quaternary Stereocenters.Journal of the American Chemical Society · 2025Article
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148 more citing papers are in PubMed but not listed here.
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Authors and funding
2 authors.
Funding
Abstract
Quaternary carbon stereocentres-carbon atoms to which four distinct carbon substituents are attached-are common features of molecules found in nature. However, before recent advances in chemical catalysis, there were few methods of constructing single stereoisomers of this important structural motif. Here we discuss the many catalytic enantioselective reactions developed during the past decade for the synthesis of single stereoisomers of such organic molecules. This progress now makes it possible to incorporate quaternary stereocentres selectively in many organic molecules that are useful in medicine, agriculture and potentially other areas such as flavouring, fragrances and materials.
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