Evidence map›Paper›PMID 25502692›Full record

ArticlePLoS neglected tropical diseases2014

A sero-epidemiological study of arboviral fevers in Djibouti, Horn of Africa.

Fred Andayi, Remi N Charrel, Alexia Kieffer, Herve Richet, Boris Pastorino, Isabelle Leparc-Goffart, Ammar Abdo Ahmed, Fabrice Carrat, Antoine Flahault, Xavier de Lamballerie

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PLoS neglected tropical diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 13 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 13 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 13 syntheses or guidelines pooled it, 70 citations in OpenAlex.

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  4. Chikungunya seroprevalence in population-based studies: a systematic review and meta-analysis.Archives of public health = Archives belges de sante publique · 2023
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  8. Chikungunya fever in Africa: a systematic review.Pathogens and global health · 2020
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  14. Article
  15. Alkhumra Hemorrhagic Fever Virus (AHFV): A Concise Overview.The Yale journal of biology and medicine · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 2 countries.

Fred AndayiAix Marseille Université, IRD French Institute of Research for Development, EHESP French School of Public Health, EPV UMR_D 190 "Emergence des Pathologies Virales", Marseille, France.
Remi N CharrelAix Marseille Université, IRD French Institute of Research for Development, EHESP French School of Public Health, EPV UMR_D 190 "Emergence des Pathologies Virales", Marseille, France; IHU Méditerranée Infection, APHM Public Hospitals of Marseille, Marseille, France.
Alexia KiefferAix Marseille Université, IRD French Institute of Research for Development, EHESP French School of Public Health, EPV UMR_D 190 "Emergence des Pathologies Virales", Marseille, France; Ecole des Hautes Etudes en Santé Publique de Rennes (EHESP), Sorbonne Paris Cité, Rennes, France.
Herve RichetAix Marseille Université, IRD French Institute of Research for Development, EHESP French School of Public Health, EPV UMR_D 190 "Emergence des Pathologies Virales", Marseille, France; IHU Méditerranée Infection, APHM Public Hospitals of Marseille, Marseille, France.
Boris PastorinoAix Marseille Université, IRD French Institute of Research for Development, EHESP French School of Public Health, EPV UMR_D 190 "Emergence des Pathologies Virales", Marseille, France; IHU Méditerranée Infection, APHM Public Hospitals of Marseille, Marseille, France.
Isabelle Leparc-GoffartFrench National Reference Centre for Arboviruses, IRBA, Marseille, France.
Ammar Abdo AhmedMinistère de la Santé, Institut National de Santé Publique, Djibouti, Republic of Djibouti.
Fabrice CarratINSERM UMR-S 707, Université Pierre et Marie Curie, Paris 6; Department of Public Health, Hôpital Saint-Antoine, AP-HP, Paris, France.
Antoine FlahaultEcole des Hautes Etudes en Santé Publique de Rennes (EHESP), Sorbonne Paris Cité, Rennes, France.
Xavier de LamballerieAix Marseille Université, IRD French Institute of Research for Development, EHESP French School of Public Health, EPV UMR_D 190 "Emergence des Pathologies Virales", Marseille, France; IHU Méditerranée Infection, APHM Public Hospitals of Marseille, Marseille, France; Ecole des Hautes Etudes en Santé Publique de Rennes (EHESP), Sorbonne Paris Cité, Rennes, France.
École des Hautes Études en Santé Publique · FRAix-Marseille Université · FRInstitut de Recherche pour le Développement · FRMéditerranée Infection Foundation · FRSorbonne Paris Cité · FRSorbonne Université · FRUniversité Paris Cité · FRUniversity of Djibouti · DJ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Arboviral infections have repeatedly been reported in the republic of Djibouti, consistent with the fact that essential vectors for arboviral diseases are endemic in the region. However, there is a limited recent information regarding arbovirus circulation, and the associated risk predictors to human exposure are largely unknown. We performed, from November 2010 to February 2011 in the Djibouti city general population, a cross-sectional ELISA and sero-neutralisation-based sero-epidemiological analysis nested in a household cohort, which investigated the arboviral infection prevalence and risk factors, stratified by their vectors of transmission. Antibodies to dengue virus (21.8%) were the most frequent. Determinants of infection identified by multivariate analysis pointed to sociological and environmental exposure to the bite of Aedes mosquitoes. The population was broadly naïve against Chikungunya (2.6%) with risk factors mostly shared with dengue. The detection of limited virus circulation was followed by a significant Chikungunya outbreak a few months after our study. Antibodies to West Nile virus were infrequent (0.6%), but the distribution of cases faithfully followed previous mapping of infected Culex mosquitoes. The seroprevalence of Rift valley fever virus was 2.2%, and non-arboviral transmission was suggested. Finally, the study indicated the circulation of Toscana-related viruses (3.7%), and a limited number of cases suggested infection by tick-borne encephalitis or Alkhumra related viruses, which deserve further investigations to identify the viruses and vectors implicated. Overall, most of the arboviral cases' predictors were statistically best described by the individuals' housing space and neighborhood environmental characteristics, which correlated with the ecological actors of their respective transmission vectors' survival in the local niche. This study has demonstrated autochthonous arboviral circulations in the republic of Djibouti, and provides an epidemiological inventory, with useful findings for risk mapping and future prevention and control programs.

Indexed as

AdolescentAdultArbovirusesArbovirus InfectionsCross-Sectional StudiesDjiboutiFemaleHumansMaleMiddle AgedSeroepidemiologic StudiesYoung Adult

Identifiers

PMID25502692
PMCPMC4263616
OpenAlexW2055494975

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.