ArticleNeuroscience bulletin2015
Grey matter volume abnormalities in patients with bipolar I depressive disorder and unipolar depressive disorder: a voxel-based morphometry study.
Article in Neuroscience bulletin, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 4 of them syntheses that pooled it.
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Who cites it
22 citing papers in PubMed, 4 syntheses or guidelines pooled it, 66 citations in OpenAlex.
- Structural rather than functional brain alterations that characterize the differences between major depressive disorder and primary insomnia: a comparative meta-analysis.BMC medicine · 2025Pooled it
- The Dark and Gloomy Brain: Grey Matter Volume Alterations in Major Depressive Disorder-Fine-Grained Meta-Analyses.Depression and anxiety · 2024Pooled it
- Pathological fear, anxiety and negative affect exhibit distinct neurostructural signatures: evidence from psychiatric neuroimaging meta-analysis.Translational psychiatry · 2022Pooled it
- Cognitive impairment and depression: Meta-analysis of structural magnetic resonance imaging studies.NeuroImage. Clinical · 2021Pooled it
- The Role of microRNA in Anaesthetics-induced Brain Injury: A Narrative Review.Turkish journal of anaesthesiology and reanimation · 2025Article
- Assessment of Brain Volume and Cortical Thickness in People with HIV and Major Depressive Disorder.Current HIV research · 2025Article
- Abnormal gray matter volume and structural covariance network of basal ganglia-limbic system in patients with major depression disorder.Frontiers in neurology · 2025Article
- Article
- Reduced Gray Matter Volume in Orbitofrontal Cortex Across Schizophrenia, Major Depressive Disorder, and Bipolar Disorder: A Comparative Imaging Study.Frontiers in neuroscience · 2022Article
- Cortical thickness distinguishes between major depression and schizophrenia in adolescents.BMC psychiatry · 2021Article
- Family history of depression is associated with alterations in task-dependent connectivity between the cerebellum and ventromedial prefrontal cortex.Depression and anxiety · 2021Article
- Healthy individualsWorld journal of clinical cases · 2021Article
- Identification of bipolar disorder using a combination of multimodality magnetic resonance imaging and machine learning techniques.BMC psychiatry · 2020Article
- Brain Imaging Study on the Pathogenesis of Depression & Therapeutic Effect of Selective Serotonin Reuptake Inhibitors.Psychiatry investigation · 2020Article
- A comparison study of metabolic profiles, immunity, and brain gray matter volumes between patients with bipolar disorder and depressive disorder.Journal of neuroinflammation · 2020Article
- Distinctive Neuroanatomical Substrates for Depression in Bipolar Disorder versus Major Depressive Disorder.Cerebral cortex (New York, N.Y. : 1991) · 2019Article
- Pattern recognition of magnetic resonance imaging-based gray matter volume measurements classifies bipolar disorder and major depressive disorder.Journal of affective disorders · 2018Article
- Topological Properties of Brain Structural Networks Represent Early Predictive Characteristics for the Occurrence of Bipolar Disorder in Patients With Major Depressive Disorder: A 7-Year Prospective Longitudinal Study.Frontiers in psychiatry · 2018Article
- Structural Asymmetry of Dorsolateral Prefrontal Cortex Correlates with Depressive Symptoms: Evidence from Healthy Individuals and Patients with Major Depressive Disorder.Neuroscience bulletin · 2016Article
- Distinct and Shared Endophenotypes of Neural Substrates in Bipolar and Major Depressive Disorders.PloS one · 2016Article
Corrections and comments
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Authors and funding
13 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bipolar disorder and unipolar depressive disorder (UD) may be different in brain structure. In the present study, we performed voxel-based morphometry (VBM) to quantify the grey matter volumes in 23 patients with bipolar I depressive disorder (BP1) and 23 patients with UD, and 23 age-, gender-, and education-matched healthy controls (HCs) using magnetic resonance imaging. We found that compared with the HC and UD groups, the BP1 group showed reduced grey matter volumes in the right inferior frontal gyrus and middle cingulate gyrus, while the UD group showed reduced volume in the right inferior frontal gyrus compared to HCs. In addition, correlation analyses revealed that the grey matter volumes of these regions were negatively correlated with the Hamilton depression rating scores. Taken together, the results of our study suggest that decreased grey matter volume of the right inferior frontal gyrus is a common abnormality in BP1 and UD, and decreased grey matter volume in the right middle cingulate gyrus may be specific to BP1.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.