Evidence map›Paper›PMID 25502371›Full record

ReviewSeminars in immunopathology2015

Immune responses to airborne fungi and non-invasive airway diseases.

Gaëlle Vacher, Hélène Niculita-Hirzel, Thierry Roger

Open access · greenAbstract readReview
PubMed Publisher
In one paragraph

Review in Seminars in immunopathology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.2field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
  2. Diagnostics (Basel, Switzerland) · 2025
    Article
  3. Article
  4. Tendency in Pulmonary Aspergillosis Investigation during the COVID-19 Era: What Is Changing?International journal of environmental research and public health · 2022
    Article
  5. Infection and drug resistance · 2022
    Article
  6. Aspergillus fumigatus and Aspergillosis in 2019.Clinical microbiology reviews · 2019
    Review
  7. Article
  8. Article
  9. Fungal Fragments and Fungal Aerosol Composition in Sawmills.Annals of work exposures and health · 2018
    Article
  10. Article
  11. Mold and Human Health: a Reality Check.Clinical reviews in allergy & immunology · 2017
    Review
  12. Article
  13. Immunity to Commensal Fungi: Detente and Disease.Annual review of pathology · 2017
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Gaëlle VacherService of Occupational Hygiene, Institute for Work and Health, University of Lausanne and Geneva, Biopole 1 Building, Corniche 2, 1066, Epalinges-Lausanne, Switzerland.
Hélène Niculita-Hirzel
Thierry Roger
University of Lausanne · CHQualis Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inhalation of fungal particles is a ubiquitous way of exposure to microorganisms during human life; however, this exposure may promote or exacerbate respiratory diseases only in particular exposure conditions and human genetic background. Depending on the fungal species and form, fungal particles can induce symptoms in the lung by acting as irritants, aeroallergens or pathogens causing infection. Some thermophilic species can even act in all these three ways (e.g. Aspergillus, Penicillium), mesophilic species being only involved in allergic and/or non-allergic airway diseases (e.g. Cladosporium, Alternaria, Fusarium). The goal of the present review is to present the current knowledge on the interaction between airborne fungal particles and the host immune system, to illustrate the differences of immune sensing of different fungal species and to emphasise the importance of conducting research on non-conventional mesophilic fungal species. Indeed, the diversity of fungal species we inhale and the complexity of their composition have a direct impact on fungal particle recognition and immune system decision to tolerate or respond to those particles, eventually leading to collateral damages promoting airway pathologies.

Indexed as

AllergensAntigens, FungalFungiGenetic Predisposition to DiseaseGenetic VariationHost-Pathogen InteractionsHumansHypersensitivityMycosesRespiratory Tract InfectionsRisk FactorsAllergensAntigens, Fungal

Identifiers

PMID25502371
OpenAlexW2029436908

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.