Evidence map›Paper›PMID 25501924›Full record

ReviewDigestive diseases and sciences2015

Hereditary and common familial colorectal cancer: evidence for colorectal screening.

N Jewel Samadder, Kory Jasperson, Randall W Burt

Abstract readReview
PubMed Publisher
In one paragraph

Review in Digestive diseases and sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Efficacy of a Telehealth Intervention on Colonoscopy Uptake When Cost Is a Barrier: The Family CARE Cluster Randomized Controlled Trial.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2015
    Trial
  3. Review
  4. Review
  5. Colorectal cancer genetic referral: Are we doing enough?Proceedings (Baylor University. Medical Center) · 2024
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Sigmoid Colon Perforation Mimics a Tuboovarian Absces.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2018
    Article
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  15. Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

N Jewel SamadderHigh Risk GI Cancers Program, Huntsman Cancer Institute, University of Utah, 2000 Circle of Hope, Salt Lake City, UT, 84112, USA, jewel.samadder@hsc.utah.edu.
Kory Jasperson
Randall W Burt

Funding

TCF/LEF function during intestinal maintenance and colon tumorigenesisP01CA073992 · NCI · UNIVERSITY OF UTAH · PI JONES, DAVID A · 1998 to 2014
$29.7M
INHERITANCE OF DISCRETE COLORECTAL ADENOMATOUS POLYPSR01CA040641 · NCI · UNIVERSITY OF UTAH · PI BURT, RANDALL WALTER · 1985 to 2007
$2.5M
NCI NIH HHS P01-CA073992NCI NIH HHS R01-CA040641PHS HHS HHSN 261201000026C
6 · The paper itself

Abstract

Colorectal cancer (CRC) is the fourth most common cancer among men and women. Between 3 and 6% of all CRCs are attributed to well-defined inherited syndromes, including Lynch syndrome, familial adenomatous polyposis, MUTYH-associated polyposis and several hamartomatous conditions. Up to 30% of CRC cases exhibit common familial risk, likely related to a combination of inherited factors and environment. Identification of these patients through family history and appropriate genetic testing can provide estimates of cancer risk that inform appropriate cancer screening, surveillance and/or preventative interventions. This article examines the colon cancer syndromes, their genetic basis, clinical management and evidence supporting colorectal screening. It also deals with the category of common (non-syndromic) familial risk including risk determination and screening guidelines.

Indexed as

Mass ScreeningAdenomatous Polyposis ColiColorectal Neoplasms, Hereditary NonpolyposisDNA GlycosylasesHumansPeutz-Jeghers SyndromeDNA GlycosylasesmutY adenine glycosylase

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.