Evidence map›Paper›PMID 25501377›Full record

ArticleThe Journal of investigative dermatology2015

Omalizumab, an Anti-IgE mAb, receives approval for the treatment of chronic idiopathic/spontaneous urticaria.

Keith C P Wu, Zarif K Jabbar-Lopez

Abstract readComment
PubMed Publisher
In one paragraph

Article in The Journal of investigative dermatology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Monoclonal Antibodies in Pediatric Atopic Dermatitis; Efficacy and Safety.Current therapeutic research, clinical and experimental · 2026
    Review
  2. Review
  3. Review
  4. Article
  5. IgE blockade with omalizumab reduces pruritus related to immune checkpoint inhibitors and anti-HER2 therapies.Annals of oncology : official journal of the European Society for Medical Oncology · 2021
    Article
  6. Article
  7. Article
  8. Dendritic Cell-Mediated Th2 Immunity and Immune Disorders.International journal of molecular sciences · 2019
    Review
  9. Biological therapies for atopic dermatitis: An update.Experimental and therapeutic medicine · 2019
    Review
  10. Article
  11. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Keith C P WuInstitute of Cellular Medicine, Medical School, Newcastle University, Newcastle, UK. Electronic address: k.c.p.wu@ncl.ac.uk.
Zarif K Jabbar-LopezInstitute of Cellular Medicine, Medical School, Newcastle University, Newcastle, UK.

Funding

Wellcome Trust
6 · The paper itself

Abstract

Omalizumab, an anti-IgE mAb, has recently been approved by the US Food and Drug Administration (FDA) and European Medicines Agency (EMA) for the treatment of chronic idiopathic urticaria. Saini et al. (2014) (this issue) report on ASTERIA I, a 40-week randomized, double-blinded, placebo-controlled phase III trial evaluating omalizumab for the treatment of this disease.

Indexed as

Anti-Allergic AgentsAntibodies, Anti-IdiotypicAntibodies, Monoclonal, HumanizedFemaleHistamine H1 AntagonistsHumansMaleOmalizumabUrticariaAnti-Allergic AgentsAntibodies, Anti-IdiotypicAntibodies, Monoclonal, HumanizedHistamine H1 AntagonistsOmalizumab

Identifiers

PMID25501377

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.