ArticlePloS one2014
High temperature increases the masculinization rate of the all-female (XX) rainbow trout "Mal" population.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9 citing papers in PubMed, 34 citations in OpenAlex.
- In-depth investigation of genome to refine QTL positions for spontaneous sex-reversal in XX rainbow trout.PloS one · 2025Article
- Unraveling the genotype by environment interaction in a thermosensitive fish with a polygenic sex determination system.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Sources of variation of DNA methylation in rainbow trout: combined effects of temperature and genetic background.Epigenetics · 2021Article
- Lessons from an unusual vertebrate sex-determining gene.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Review
- Characteristics and Cryopreservation of Semen of Sex-Reversed Females of Salmonid Fish.International journal of molecular sciences · 2021Review
- Development of supermale and all-male Atlantic salmon to research the vgll3 allele - puberty link.BMC genetics · 2020Article
- Genetic determinism of spontaneous masculinisation in XX female rainbow trout: new insights using medium throughput genotyping and whole-genome sequencing.Scientific reports · 2020Article
- Transcriptome Profiling Insights the Feature of Sex Reversal Induced by High Temperature in Tongue SoleFrontiers in genetics · 2019Article
- Genomic Instability of the Sex-Determining Locus in Atlantic Salmon (Salmo salar).G3 (Bethesda, Md.) · 2015Article
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10 authors at 3 institutions in 1 country.
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Abstract
Salmonids are generally considered to have a robust genetic sex determination system with a simple male heterogamety (XX/XY). However, spontaneous masculinization of XX females has been found in a rainbow trout population of gynogenetic doubled haploid individuals. The analysis of this masculinization phenotype transmission supported the hypothesis of the involvement of a recessive mutation (termed mal). As temperature effect on sex differentiation has been reported in some salmonid species, in this study we investigated in detail the potential implication of temperature on masculinization in this XX mal-carrying population. Seven families issued from XX mal-carrying parents were exposed from the time of hatching to different rearing water temperatures ((8, 12 and 18°C), and the resulting sex-ratios were confirmed by histological analysis of both gonads. Our results demonstrate that masculinization rates are strongly increased (up to nearly two fold) at the highest temperature treatment (18°C). Interestingly, we also found clear differences between temperatures on the masculinization of the left versus the right gonads with the right gonad consistently more often masculinized than the left one at lower temperatures (8 and 12°C). However, the masculinization rate is also strongly dependent on the genetic background of the XX mal-carrying families. Thus, masculinization in XX mal-carrying rainbow trout is potentially triggered by an interaction between the temperature treatment and a complex genetic background potentially involving some part of the genetic sex differentiation regulatory cascade along with some minor sex-influencing loci. These results indicate that despite its rather strict genetic sex determinism system, rainbow trout sex differentiation can be modulated by temperature, as described in many other fish species.
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