ArticleScientific reports2014
Liquid but durable: molecular dynamics simulations explain the unique properties of archaeal-like membranes.
Article in Scientific reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed, 58 citations in OpenAlex.
- Article
- Structure Diversity and Properties of Some Bola-like Natural Products.Marine drugs · 2024Review
- The biophysics of water in cell biology: perspectives on a keystone for both marine sciences and cancer research.Frontiers in cell and developmental biology · 2024Article
- Vesicular and Planar Membranes of Archaea Lipids: Unusual Physical Properties and Biomedical Applications.International journal of molecular sciences · 2022Review
- Bacterial Membranes Are More Perturbed by the Asymmetric Versus Symmetric Loading of Amphiphilic Molecules.Membranes · 2022Article
- Enantioselective Total Synthesis of the Archaeal Lipid Parallel GDGT-0 (Isocaldarchaeol)*.Angewandte Chemie (International ed. in English) · 2021Article
- Mechanical properties of ester- and ether-DPhPC bilayers: A molecular dynamics study.Journal of the mechanical behavior of biomedical materials · 2021Article
- A Novel Approach to Characterize the Lipidome of Marine ArchaeonFrontiers in microbiology · 2021Article
- Adaptations of archaeal and bacterial membranes to variations in temperature, pH and pressure.Extremophiles : life under extreme conditions · 2017Review
- Article
- On the Archaeal Origins of Eukaryotes and the Challenges of Inferring Phenotype from Genotype.Trends in cell biology · 2016Review
- Biological Membranes in Extreme Conditions: Simulations of Anionic Archaeal Tetraether Lipid Membranes.PloS one · 2016Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Archaeal plasma membranes appear to be extremely durable and almost impermeable to water and ions, in contrast to the membranes of Bacteria and Eucaryota. Additionally, they remain liquid within a temperature range of 0-100°C. These are the properties that have most likely determined the evolutionary fate of Archaea, and it may be possible for bionanotechnology to adopt these from nature. In this work, we use molecular dynamics simulations to assess at the atomistic level the structure and dynamics of a series of model archaeal membranes with lipids that have tetraether chemical nature and "branched" hydrophobic tails. We conclude that the branched structure defines dense packing and low water permeability of archaeal-like membranes, while at the same time ensuring a liquid-crystalline state, which is vital for living cells. This makes tetraether lipid systems promising in bionanotechnology and material science, namely for design of new and unique membrane nanosystems.
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