Evidence map›Paper›PMID 25501020›Full record

ReviewCurrent opinion in critical care2015

Prevention of acute respiratory distress syndrome.

Emir Festic, Daryl J Kor, Ognjen Gajic

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Current opinion in critical care, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02759770 (Risk Factors and Prediction Score of ARDS After Cardiac Surgery), which is not on this map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02759770 completednot on this mapstarted 2017, after this paper: background citation

Risk Factors and Prediction Score of ARDS After Cardiac Surgery

TypeobservationalSponsorBeijing Anzhen HospitalRan2017 to 2017Enrolled1,333ConditionsRespiratory Distress Syndrome, Adult, Thoracic Surgery, Risk FactorsArmsno intervention
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 30 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. L-carnitine reduces acute lung injury via mitochondria modulation and inflammation control in pulmonary macrophages.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2023
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. [Interactions between lung and kidney in the critically ill].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2018
    Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Emir FesticaPulmonary and Critical Care Medicine, Mayo Clinic, Jacksonville, Florida bAnesthesiology and Critical Care Medicine cPulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Daryl J Kor
Ognjen Gajic
Jacksonville College · USMayo Clinic · US

Funding

Mayo Clinic Center for Translational Science ActivitiesUL1TR000135 · NCATS · MAYO CLINIC ROCHESTER · PI KHOSLA, SUNDEEP · 2012 to 2015
$41.2M
Mayo Clinic Center for Translational Science ActivitiesKL2TR000136 · NCATS · MAYO CLINIC ROCHESTER · PI KHOSLA, SUNDEEP · 2012 to 2015
$6.6M
LIPS-A: Lung Injury Prevention Study with AspirinU01HL108712 · NHLBI · MAYO CLINIC ROCHESTER · PI GAJIC, OGNJEN, GONG, MICHELLE NG · 2011 to 2013
$6.1M
Risk Prediction and Mechanistic Evaluation of Postoperative Acute Lung InjuryK23HL112855 · NHLBI · MAYO CLINIC ROCHESTER · PI KOR, DARYL J · 2012 to 2014
$393k
NCATS NIH HHS 5KL2 TR000136NCATS NIH HHS KL2 TR000136NCATS NIH HHS TR00135-09JNCATS NIH HHS UL1 TR000135NHLBI NIH HHS K23 HL112855NHLBI NIH HHS K23 HL112855-02NHLBI NIH HHS U01 HL108712NHLBI NIH HHS U01 HL108712-01
6 · The paper itself

Abstract

purpose of reviewThe paucity of effective therapeutic interventions in patients with the acute respiratory distress syndrome (ARDS) combined with overwhelming evidence on the importance of timely implementation of effective therapies to critically ill patients has resulted in a recent shift in ARDS research. Increasingly, efforts are being directed toward early identification of patients at risk with a goal of prevention and early treatment, prior to development of the fully established syndrome. The focus of the present review is on the prevention of ARDS in patients without this condition at the time of their healthcare encounter. RECENT

findingsThe primary thematic categories presented in the present review article include early identification of patients at risk of developing ARDS, optimization of care delivery and its impact on the incidence of ARDS, pharmacological prevention of ARDS, prevention of postoperative ARDS, and challenges and opportunities with ARDS prevention studies. SUMMARY: Recent improvements in clinical care delivery have been associated with a decrease in the incidence of hospital-acquired ARDS. Despite the initial challenges, research in ARDS prevention has become increasingly feasible with several randomized controlled trials on ARDS prevention completed or on the way.

Indexed as

Anti-Inflammatory AgentsCritical IllnessHumansLung InjuryPatient CareRespiration, ArtificialRespiratory Distress SyndromeAnti-Inflammatory Agents

Identifiers

PMID25501020
PMCPMC4431656
OpenAlexW1980513483

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.