Evidence map›Paper›PMID 25500871›Full record

ReviewActa pharmacologica Sinica2015

The use of marine-derived bioactive compounds as potential hepatoprotective agents.

Dileep G Nair, Ralf Weiskirchen, Salma K Al-Musharafi

Open access · bronzeAbstract readReview
In one paragraph

Review in Acta pharmacologica Sinica, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 46 citations in OpenAlex.

  1. Review
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  7. Manzamine-A AltersJournal of natural products · 2024
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  19. ABioMed research international · 2018
    Article
  20. Resveratrol prevents protein nitration and release of endonucleases from mitochondria during acetaminophen hepatotoxicity.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Dileep G NairDepartment of Applied Biotechnology, Sur College of Applied Sciences, Ministry of Higher Education, Sur, Sultanate of Oman.
Ralf WeiskirchenInstitute of Clinical Chemistry and Pathobiochemistry, RWTH University Hospital Aachen, Aachen, Germany.
Salma K Al-MusharafiDepartment of Applied Biotechnology, Sur College of Applied Sciences, Ministry of Higher Education, Sur, Sultanate of Oman.
Sur University College · OMUniversitätsklinikum Aachen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The marine environment may be explored as a rich source for novel drugs. A number of marine-derived compounds have been isolated and identified, and their therapeutic effects and pharmacological profiles are characterized. In the present review, we highlight the recent studies using marine compounds as potential hepatoprotective agents for the treatment of liver fibrotic diseases and discuss the proposed mechanisms of their activities. In addition, we discuss the significance of similar studies in Oman, where the rich marine life provides a potential for the isolation of novel natural, bioactive products that display therapeutic effects on liver diseases.

Indexed as

AnimalsBiological ProductsHumansLiverLiver DiseasesProtective AgentsBiological ProductsProtective Agents

Identifiers

PMID25500871
PMCPMC4326787
OpenAlexW2037095717

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.