Evidence map›Paper›PMID 25500348›Full record

Trial reportPsychiatry research2015

Living with tics: reduced impairment and improved quality of life for youth with chronic tic disorders.

Joseph F McGuire, Elysse Arnold, Jennifer M Park, Joshua M Nadeau, Adam B Lewin, Tanya K Murphy, Eric A Storch

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Psychiatry research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02900144 (Modified Comprehensive Behavioral Intervention for Tics), which is not on this map. Cited by 38 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 4 pooled it
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02900144 nacompletednot on this mapstarted 2016, after this paper: background citation

Modified Comprehensive Behavioral Intervention for Tics: Treating Children With Tic Disorders, Co-occurring ADHD and Psychosocial Impairment

TypeinterventionalSponsorMassachusetts General HospitalRan2016 to 2019Enrolled17ConditionsTourette Syndrome, ADHDArmsModified Comprehensive Behavioral Intervention for Tics, Comprehensive Behavioral Intervention for Tics
3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 4 syntheses or guidelines pooled it, 104 citations in OpenAlex.

  1. Guideline
  2. Pooled it
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  4. Pooled it
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  11. Quality of Life in Children and Youth with Obsessive-Compulsive Disorder.Journal of child and adolescent psychopharmacology · 2018
    Trial
  12. Clinical Predictors of Tic-Related Impairment in Children and Adults with Tourette Syndrome.Movement disorders : official journal of the Movement Disorder Society · 2026
    Article
  13. Article
  14. Evidence-Based Behavior Therapy for Tourette Syndrome.The Psychiatric clinics of North America · 2025
    Review
  15. Reframing stigma in Tourette syndrome: an updated scoping review.European child & adolescent psychiatry · 2025
    Article
  16. Article
  17. Sleep Disorders, Sleep Medication Use, and Predictors of Sleep Disturbance in Children with Persistent Tic Disorders.Children's health care : journal of the Association for the Care of Children's Health · 2024
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Joseph F McGuireDepartment of Psychology, University of South Florida, Tampa, FL, USA; Department of Pediatrics, University of South Florida, Tampa, FL, USA. Electronic address: jfmcguire@mail.usf.edu.
Elysse ArnoldDepartment of Psychology, University of South Florida, Tampa, FL, USA; Department of Pediatrics, University of South Florida, Tampa, FL, USA.
Jennifer M ParkDepartment of Psychology, University of South Florida, Tampa, FL, USA; Department of Pediatrics, University of South Florida, Tampa, FL, USA.
Joshua M NadeauDepartment of Pediatrics, University of South Florida, Tampa, FL, USA.
Adam B LewinDepartment of Psychology, University of South Florida, Tampa, FL, USA; Department of Pediatrics, University of South Florida, Tampa, FL, USA; Departments of Psychiatry and Behavioral Neurosciences, University of South Florida, Tampa, FL, USA.
Tanya K MurphyDepartment of Pediatrics, University of South Florida, Tampa, FL, USA; Departments of Psychiatry and Behavioral Neurosciences, University of South Florida, Tampa, FL, USA; All Children׳s Hospital - Johns Hopkins Medicine, St. Petersburg, FL, USA.
Eric A StorchDepartment of Psychology, University of South Florida, Tampa, FL, USA; Department of Pediatrics, University of South Florida, Tampa, FL, USA; Departments of Psychiatry and Behavioral Neurosciences, University of South Florida, Tampa, FL, USA; Roger׳s Behavioral Health - Tampa Bay, Tampa, FL, USA; All Children׳s Hospital - Johns Hopkins Medicine, St. Petersburg, FL, USA.
University of South Florida · USJohns Hopkins All Children's Hospital · US

Funding

1/2-D-Cycloserine Augmentation of CBT for Pediatric OCDR01MH093381 · NIMH · UNIVERSITY OF SOUTH FLORIDA · PI STORCH, ERIC A. · 2011 to 2014
$1.2M
NIMH NIH HHS R01 MH093381NIMH NIH HHS R01MH093381
6 · The paper itself

Abstract

Pharmacological and behavioral interventions have focused on reducing tic severity to alleviate tic-related impairment for youth with chronic tic disorders (CTDs), with no existing intervention focused on the adverse psychosocial consequences of tics. This study examined the preliminary efficacy of a modularized cognitive behavioral intervention ("Living with Tics", LWT) in reducing tic-related impairment and improving quality of life relative to a waitlist control of equal duration. Twenty-four youth (ages 7-17 years) with Tourette Disorder or Chronic Motor Tic Disorder and psychosocial impairment participated. A treatment-blind evaluator conducted all pre- and post-treatment clinician-rated measures. Youth were randomly assigned to receive the LWT intervention (n=12) or a 10-week waitlist (n=12). The LWT intervention consisted of up to 10 weekly sessions targeted at reducing tic-related impairment and developing skills to manage psychosocial consequences of tics. Youth in the LWT condition experienced significantly reduced clinician-rated tic-impairment, and improved child-rated quality of life. Ten youth (83%) in the LWT group were classified as treatment responders compared to four youth in the waitlist condition (33%). Treatment gains were maintained at one-month follow-up. Findings provide preliminary data that the LWT intervention reduces tic-related impairment and improves quality of life for youth with CTDs.

Indexed as

Adaptation, PsychologicalQuality of LifeAdolescentBehavior TherapyChildChronic DiseaseCognitive Behavioral TherapyFemaleHumansMaleParentsProblem SolvingSingle-Blind MethodTic DisordersTourette SyndromeChronic tic disordersCognitive behavior therapyFunctional impairmentQuality of lifeTourette DisorderTreatment outcome

Identifiers

PMID25500348
PMCPMC4314444
OpenAlexW2114183635

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.