Evidence map›Paper›PMID 25499686›Full record

ArticleJournal of affective disorders2015

Anxiety comorbidity in bipolar spectrum disorders: the mediational role of perfectionism in prospective depressive symptoms.

Jared K O'Garro-Moore, Ashleigh Molz Adams, Lyn Y Abramson, Lauren B Alloy

Abstract read
In one paragraph

Article in Journal of affective disorders, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Jared K O'Garro-MooreTemple University, United States.
Ashleigh Molz AdamsTemple University, United States.
Lyn Y AbramsonUniversity of Wisconsin-Madison, United States.
Lauren B AlloyTemple University, United States. Electronic address: lalloy@temple.edu.
Temple University · USTemple College · USUniversity of Wisconsin–Madison · US

Funding

Risk for Bipolar Disorder: Reward-related Brain Function & Social RhythmsR01MH077908 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI ALLOY, LAUREN BERSH · 2007 to 2017
$5.7M
Behavioral Approach System (BAS)and Bipolar Spectrum: Biopsychosocial IntegrationR01MH052617 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI ALLOY, LAUREN BERSH · 2003 to 2007
$2.2M
BAS and Bipolar Spectrum: Biopsychosocial IntegrationR01MH052662 · NIMH · UNIVERSITY OF WISCONSIN-MADISON · PI ABRAMSON, LYN Y · 2003 to 2007
$2.1M
Social and Circadian Rhythms, Reward Sensitivity, and Risk for Bipolar DisorderR01MH102310 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI ALLOY, LAUREN BERSH · 2014 to 2017
$1.6M
COURSE OF CYCLOTHYMIA--ROLE COGNITION AND STRESSR10MH052662 · NIMH · UNIVERSITY OF WISCONSIN MADISON · PI ABRAMSON, LYN Y · 1997 to 2001
$1.1M
COURSE OF CYCLOTHYMIA--ROLE OF COGNITION AND STRESSR10MH052617 · NIMH · TEMPLE UNIVERSITY · PI ALLOY, LAUREN BERSH · 1997 to 2001
$1.0M
NIMH NIH HHS MH102310NIMH NIH HHS MH52617NIMH NIH HHS MH52662NIMH NIH HHS MH77908NIMH NIH HHS R01 MH052617NIMH NIH HHS R01 MH052662NIMH NIH HHS R01 MH077908NIMH NIH HHS R01 MH102310NIMH NIH HHS R10 MH052617NIMH NIH HHS R10 MH052662
6 · The paper itself

Abstract

backgroundBipolar spectrum disorders (BSDs) are highly comorbid with anxiety, which is associated with an extended duration and exacerbation of depressive symptoms. Unfortunately, the underlying mechanisms are not known. This study examined the role of maladaptive cognitive styles in the co-occurrence of BSDs and anxiety disorders and prediction of depressive symptoms.

methodsParticipants included 141 young adults (69.6% female, mean age=20.24, SD=2.11), in one of three groups: a BSD group (bipolar II, cyclothymia, n=48), a comorbid BSD/anxiety group (n=50), and a demographically-matched healthy control group (n=43), who were followed prospectively. Participants completed the Cognitive Style Questionnaire (CSQ), Depressive Experiences Questionnaire (DEQ), Dysfunctional Attitudes Scale (DAS), Sociotropy Autonomy Scale (SAS), Halberstadt Mania Inventory (HMI) and Beck Depression Inventory (BDI) at the initial assessment. One year later, participants completed the BDI and HMI again to assess severity of depressive and hypomanic/manic symptoms.

resultsA multivariate analysis of co-variance (MANCOVA) revealed significant differences between the three groups on their DAS Perfectionism, DEQ Dependency, DEQ Self-Criticism, CSQ Negative, SAS Autonomy, and Time 2 BDI scores, with the BSD/anxiety group scoring higher than the BSD only group on all measures except the CSQ. Preacher and Hayes׳ (2008) bootstrapping method was used to test for mediational effects of the significant cognitive style measures on depressive symptoms at follow-up. The 95% confidence intervals for the indirect effect of group on follow-up depressive symptoms through DAS Perfectionism did not include zero, indicating the presence of a significant mediating relationship for perfectionism. LIMITATIONS: This study only used two waves of data; three waves of data would allow one to investigate the full causal effect of one variable on another. Further, a comorbid anxiety diagnosis consisted of any anxiety disorder. Further research should separate groups by their specific anxiety diagnoses; this could afford a more complete understanding of the effect of types of anxiety on prospective depressive symptoms.

conclusionsAfter taking into account initial levels of depressive and hypomanic/manic symptoms, we found that those with BSD/anxiety comorbidity experienced more severe depressive symptoms, but not more severe hypomanic/manic symptoms. Further, their more severe prospective depressive symptoms are explained by a perfectionistic cognitive style.

Indexed as

PersonalityAdultAnxietyAnxiety DisordersBipolar DisorderCase-Control StudiesComorbidityCyclothymic DisorderDepressionFemaleHumansMalePersonality InventoryPredictive Value of TestsProspective StudiesPsychiatric Status Rating ScalesAnxietyBipolar disorderCognitive stylesComorbidity

Identifiers

PMID25499686
PMCPMC4986825
OpenAlexW2120195793

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.