Evidence map›Paper›PMID 25499259›Full record

ArticleAmerican journal of obstetrics and gynecology2015

Uterine sarcomas and parasitic myomas after laparoscopic hysterectomy with power morcellation.

Jasmine Tan-Kim, Katherine A Hartzell, Caryl S Reinsch, Cristina H O'Day, John S Kennedy, Shawn A Menefee, Terry A Harrison

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Article in American journal of obstetrics and gynecology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Leiomyosarcoma Occurring After Hysterectomy for Benign Fibroids: A Case Report.Journal of obstetrics and gynaecology of India · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Morcellation of the Uterus: Is There Any Place?Current oncology reports · 2020
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Is Laparoscopic Power Morcellation of Fibroids a Cardinal Sin in 2017?Journal of obstetrics and gynaecology of India · 2017
    Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Jasmine Tan-KimDivision of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics and Gynecology, Kaiser Permanente San Diego, San Diego, CA. Electronic address: Jasmine.X.Tan-Kim@kp.org.
Katherine A HartzellDepartment of Obstetrics and Gynecology, Kaiser Permanente San Diego, San Diego, CA.
Caryl S ReinschDepartment of Obstetrics and Gynecology, Kaiser Permanente San Diego, San Diego, CA.
Cristina H O'DayDepartment of Obstetrics and Gynecology, St. Joseph Hospital, Orange, CA.
John S KennedyDepartment of Obstetrics and Gynecology, Kaiser Permanente San Diego, San Diego, CA.
Shawn A MenefeeDivision of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics and Gynecology, Kaiser Permanente San Diego, San Diego, CA.
Terry A HarrisonDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Kaiser Permanente San Diego, San Diego, CA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe purpose of this study was to describe the incidence and risk factors for uterine sarcomas and parasitic myomas at the time of power morcellation. STUDY

designWe performed a retrospective review of 3523 women who underwent laparoscopic hysterectomy from 2001-2012. Univariate analyses were used for the morcellation cases to identify potential risk factors. Multivariable logistic regression was performed.

resultsNine hundred forty-one patients underwent power morcellation at the time of hysterectomy; 10 of 941 patients (1.1%) were diagnosed subsequently with uterine sarcomas or parasitic myomas. The overall incidence of uterine sarcoma was 6 of 941 (0.6%), with a median age of 47 years (range, 41-52 years). There was no association among any of the factors analyzed and uterine sarcoma. Three of 6 patients had sarcoma diagnosed on initial pathologic evaluation of the morcellated specimen; 3 patients had delayed diagnosis of sarcoma with benign disease at the time of the initial procedure (median time to second evaluation, 6 years). For parasitic myomas (n=4), the median age was 35 years (range, 32-40 years), and the median time to second evaluation was 5 years. On multivariate analysis, age<40 years (odds ratio, 26; 95% confidence interval, 2.7015-261.9; P≤.01) was associated with higher risk of the development of parasitic myomas.

conclusionUterine sarcoma was found in 0.6% of patients who underwent power morcellation but was not found to be associated significantly with any preoperative factors. All 6 cases were noted to have apparent fibroid tumors as an indication for their hysterectomy. Age<40 years was a risk factor for parasitic myomas after power morcellation. Patients should be counseled about these complications before power morcellation.

Indexed as

AdultAge FactorsFemaleHumansHysterectomyLaparoscopyLeiomyomaLogistic ModelsMiddle AgedMultivariate AnalysisRetrospective StudiesRisk FactorsSarcomaUterine Neoplasmslaparoscopic hysterectomyparasitic myomaspower morcellationuterine sarcoma

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.