Evidence map›Paper›PMID 25499058›Full record

ArticleAmerican journal of hypertension2015

Prevalence, Determinants, and Clinical Significance of Masked Hypertension in a Population-Based Sample of African Americans: The Jackson Heart Study.

Keith M Diaz, Praveen Veerabhadrappa, Michael D Brown, Matthew C Whited, Patricia M Dubbert, DeMarc A Hickson

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in American journal of hypertension, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 3 pooled it
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 3 syntheses or guidelines pooled it, 85 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Disparities in Blood Pressure Measurement.Current hypertension reports · 2026
    Review
  5. Article
  6. Blood Pressure and Heart Rate Response to Orthostasis in Somali Americans.Journal of racial and ethnic health disparities · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. The association between depressive symptoms and masked hypertension in participants with normotension measured at research center.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Article
  12. Review
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  18. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 1 country.

Keith M DiazCenter for Behavioral Cardiovascular Health, Department of Medicine, Columbia University Medical Center, New York, New York, USA; kd2442@columbia.edu.
Praveen VeerabhadrappaDepartment of Exercise Science, Shippensburg University, Shippensburg, Pennsylvania, USA;
Michael D BrownVascular Health Laboratory, Department of Kinesiology & Nutrition, University of Illinois at Chicago, Chicago, Illinois, USA;
Matthew C WhitedDepartment of Psychology, East Carolina University, Greenville, North Carolina, USA;
Patricia M Dubbert
DeMarc A HicksonJackson Heart Study, Jackson State University, Jackson, Mississippi, USA; Department of Medicine, University of Mississippi Medical Center, Jackson, Mississippi, USA.
Columbia University Irving Medical Center · USEast Carolina University · USJackson State University · USShippensburg University · USUniversity of Arkansas for Medical Sciences · USUniversity of Illinois Chicago · US

Funding

WORKSITE BLOOD PRESSURE STUDYP01HL047540 · NHLBI · WEILL MEDICAL COLLEGE OF CORNELL UNIV · PI SCHWARTZ, JOSEPH E · 1993 to 2014
$27.7M
Incorporation of a Hypertension Working Group into the Jackson Heart StudyR01HL117323 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LEWIS, CORA E, OGEDEGBE, OLUGBENGA G. · 2013 to 2024
$7.2M
JACKSON HEART STUDY--EXAM CENTERN01HC095171 · HC · UNIVERSITY OF MISSISSIPPI MEDICAL CENTER · PI JONES, DANIEL W · 1999 to 2001
$4.6M
Translational Research of Negative Emotions and Acute Endothelial DysfunctionR01HL116470 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SHIMBO, DAICHI · 2013 to 2017
$3.0M
Depression treatment and risk for cardiovascular diseaseK23HL109620 · NHLBI · EAST CAROLINA UNIVERSITY · PI WHITED, MATTHEW CHARLES · 2012 to 2016
$646k
JACKSON HEART STUDY--TRAINING CENTERN01HC095172 · HC · TOUGALOO COLLEGE · PI SRINIVASAN, ASOKA · 1999 to 2001
$516k
Development of a humanized anti-CD47 antibody for treatment of tissue ischemia.R41HL095172 · NHLBI · VASCULOX, INC. · PI FRAZIER, WILLIAM A · 2009 to 2009
$198k
JACKSON HEART STUDY-N01HC95170N01HC095170 · HC · JACKSON STATE UNIVERSITY · PI TAYLOR, HERMAN ALFRED · 1999 to 2006
$20k
NHLBI NIH HHS K23 HL109620NHLBI NIH HHS N01 HC095170NHLBI NIH HHS N01 HC095171NHLBI NIH HHS N01 HC095172NHLBI NIH HHS N01-HC-95170NHLBI NIH HHS N01-HC-95171NHLBI NIH HHS N01-HC-95172NHLBI NIH HHS P01 HL047540NHLBI NIH HHS P01-HL047540-19S1NHLBI NIH HHS R01 HL116470NHLBI NIH HHS R01-HL116470-02S1NHLBI NIH HHS R01 HL117323NHLBI NIH HHS R01-HL117323
6 · The paper itself

Abstract

backgroundThe disproportionate rates of cardiovascular disease in African Americans may, in part, be due to suboptimal assessment of blood pressure (BP) with clinic BP measurements alone. To date, however, the prevalence of masked hypertension in African Americans has not been fully delineated. The purpose of this study was to evaluate masked hypertension prevalence in a large population-based sample of African Americans and examine its determinants and association with indices of target organ damage (TOD).

methodsClinic and 24-hour ambulatory BP monitoring were conducted in 972 African Americans enrolled in the Jackson Heart Study. Common carotid artery intima-media thickness, left ventricular mass index, and the urinary albumin:creatinine excretion ratio were evaluated as indices of TOD.

resultsMasked hypertension prevalence was 25.9% in the overall sample and 34.4% in participants with normal clinic BP. All indices of TOD were significantly higher in masked hypertensives compared to sustained normotensives and were similar between masked hypertensives and sustained hypertensives. Male gender, smoking, diabetes, and antihypertensive medication use were independent determinants of masked hypertension in multivariate analyses.

conclusionsIn this population-based cohort of African Americans, approximately one-third of participants with presumably normal clinic BP had masked hypertension when BP was assessed in their daily environment. Masked hypertension was accompanied by a greater degree of TOD in this cohort.

Indexed as

Black or African AmericanBlood PressureAgedAntihypertensive AgentsBlood Pressure Monitoring, AmbulatoryCarotid Artery, CommonCarotid Artery DiseasesCarotid Intima-Media ThicknessDiabetes MellitusDisease ProgressionFemaleHumansHypertrophy, Left VentricularKidney DiseasesLogistic ModelsMaleAntihypertensive AgentsAfrican Americansambulatory blood pressure monitoringblood pressurehypertensionmasked hypertensiontarget organ damage.

Identifiers

PMID25499058
PMCPMC4481565
OpenAlexW2128363282

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.