Observational studyInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2015
Prognosis of neonatal tetanus in the modern management era: an observational study in 107 Vietnamese infants.
Observational study in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 30 citations in OpenAlex.
- Neonatal tetanus in undocumented migrant families in Saudi Arabia: outcomes and critical care resource utilization in a 10-year tertiary PICU cohort.Frontiers in pediatrics · 2026Article
- Successful management of neonatal tetanus with autonomic manifestations at a referral hospital in Nigeria: a case report.BMC pediatrics · 2025Article
- Neonatal tetanus in South Sudan: a case series.African health sciences · 2024Article
- Heart Rate Variability Measured from Wearable Devices as a Marker of Disease Severity in Tetanus.The American journal of tropical medicine and hygiene · 2024Article
- Seroprotection against tetanus in southern Vietnam.Vaccine · 2023Article
- Classification of Tetanus Severity in Intensive-Care Settings for Low-Income Countries Using Wearable Sensing.Sensors (Basel, Switzerland) · 2022Article
- Neonatal tetanus with good outcomes at a regional referral hospital in Eastern Uganda: a case report.Journal of medical case reports · 2022Article
- Severity detection tool for patients with infectious disease.Healthcare technology letters · 2020Article
- Long-term outcome in survivors of neonatal tetanus following specialist intensive care in Vietnam.BMC infectious diseases · 2017Article
- Tetanus in Southern Vietnam: Current Situation.The American journal of tropical medicine and hygiene · 2017Article
- Neonatal Tetanus in Vietnam: Comprehensive Intensive Care Support Improves Mortality.Journal of the Pediatric Infectious Diseases Society · 2016Article
- Eradication of tetanus.British medical bulletin · 2015Review
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 4 countries.
Funding
Abstract
objectivesMost data regarding the prognosis in neonatal tetanus originate from regions where limited resources have historically impeded management. It is not known whether recent improvements in critical care facilities in many low- and middle-income countries have affected indicators of a poor prognosis in neonatal tetanus. We aimed to determine the factors associated with worse outcomes in a Vietnamese hospital with neonatal intensive care facilities.
methodsData were collected from 107 cases of neonatal tetanus. Clinical features on admission were analyzed against mortality and a combined endpoint of 'death or prolonged hospital stay'.
resultsMultivariable analysis showed that only younger age (odds ratio (OR) for mortality 0.69, 95% confidence interval (CI) 0.48-0.98) and lower weight (OR for mortality 0.06, 95% CI 0.01-0.54) were significantly associated with both the combined endpoint and death. A shorter period of onset (OR 0.94, 95% CI 0.88-0.99), raised white cell count (OR 1.17, 95% CI 1.02-1.35), and time between first symptom and admission (OR 3.77, 95% CI 1.14-12.51) were also indicators of mortality.
conclusionsRisk factors for a poor outcome in neonatal tetanus in a setting with critical care facilities include younger age, lower weight, delay in admission, and leukocytosis.
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