ArticleNeurobiology of learning and memory2015
REM sleep rescues learning from interference.
Article in Neurobiology of learning and memory, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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Who cites it
46 citing papers in PubMed.
- The role of sleep and wakefulness in the recognition of emotional pictures.Journal of sleep research · 2022Trial
- Recovery sleep after total sleep deprivation preserves neutral and enhances emotional declarative memory.Sleep advances : a journal of the Sleep Research Society · 2026Article
- The Role of Rapid Eye Movement Sleep in Neural Differentiation of Memories in the Hippocampus.Journal of cognitive neuroscience · 2026Article
- Article
- Cholinergic modulation of neural networks supports sequential and complementary roles for NREM and REM states in memory consolidation.PLoS computational biology · 2025Article
- REM refines and rescues memory representations: a new theory.Sleep advances : a journal of the Sleep Research Society · 2025Review
- Memory Reactivation during Sleep Does Not Act Holistically on Object Memory.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- When memories get complex, sleep comes to their rescue.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Memory reactivation during sleep does not act holistically on object memory.bioRxiv : the preprint server for biology · 2024Article
- Plasticity-stability dynamics during post-training processing of learning.Trends in cognitive sciences · 2024Review
- The phase of plasticity-induced neurochemical changes of high-frequency repetitive transcranial magnetic stimulation are different from visual perceptual learning.Scientific reports · 2023Article
- A nap consolidates generalized perceptual learning.Frontiers in sleep · 2023Article
- Sleep strengthens resting-state functional communication between brain areas involved in the consolidation of problem-solving skills.Learning & memory (Cold Spring Harbor, N.Y.) · 2023Article
- A neural network account of memory replay and knowledge consolidation.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- Sleep-like unsupervised replay reduces catastrophic forgetting in artificial neural networks.Nature communications · 2022Article
- A failure of sleep-dependent consolidation of visuoperceptual procedural learning in young adults with ADHD.Translational psychiatry · 2022Article
- A model of autonomous interactions between hippocampus and neocortex driving sleep-dependent memory consolidation.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Sleep prevents catastrophic forgetting in spiking neural networks by forming a joint synaptic weight representation.PLoS computational biology · 2022Article
- Replay in Deep Learning: Current Approaches and Missing Biological Elements.Neural computation · 2021Article
- The Black Box effect: sensory stimulation after learning interferes with the retention of long-term object location memory in rats.Learning & memory (Cold Spring Harbor, N.Y.) · 2021Article
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3 authors.
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Abstract
Classical human memory studies investigating the acquisition of temporally-linked events have found that the memories for two events will interfere with each other and cause forgetting (i.e., interference; Wixted, 2004). Importantly, sleep helps consolidate memories and protect them from subsequent interference (Ellenbogen, Hulbert, Stickgold, Dinges, & Thompson-Schill, 2006). We asked whether sleep can also repair memories that have already been damaged by interference. Using a perceptual learning paradigm, we induced interference either before or after a consolidation period. We varied brain states during consolidation by comparing active wake, quiet wake, and naps with either non-rapid eye movement sleep (NREM), or both NREM and REM sleep. When interference occurred after consolidation, sleep and wake both produced learning. However, interference prior to consolidation impaired memory, with retroactive interference showing more disruption than proactive interference. Sleep rescued learning damaged by interference. Critically, only naps that contained REM sleep were able to rescue learning that was highly disrupted by retroactive interference. Furthermore, the magnitude of rescued learning was correlated with the amount of REM sleep. We demonstrate the first evidence of a process by which the brain can rescue and consolidate memories damaged by interference, and that this process requires REM sleep. We explain these results within a theoretical model that considers how interference during encoding interacts with consolidation processes to predict which memories are retained or lost.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.