Evidence map›Paper›PMID 25497723›Full record

ArticleJournal of stroke and cerebrovascular diseases : the official journal of National Stroke Association2015

Family history of stroke and cardiovascular health in a national cohort.

Ambar Kulshreshtha, Viola Vaccarino, Abhinav Goyal, William McClellan, Fadi Nahab, Virginia J Howard, Suzanne E Judd

Open access · greenAbstract read
In one paragraph

Article in Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 24 citations in OpenAlex.

  1. A Cluster-Randomized Evaluation of the SuperShelf Intervention in Choice-Based Food Pantries.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2024
    Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. Diagnostics (Basel, Switzerland) · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Ambar KulshreshthaDepartment of Epidemiology, Emory University, Atlanta, Georgia; Department of Family and Preventive Medicine, Emory University, Atlanta, Georgia. Electronic address: akulshr@emory.edu.
Viola VaccarinoDepartment of Epidemiology, Emory University, Atlanta, Georgia; Department of Medicine, Emory University, Atlanta, Georgia.
Abhinav GoyalDepartment of Medicine, Emory University, Atlanta, Georgia.
William McClellanDepartment of Epidemiology, Emory University, Atlanta, Georgia.
Fadi NahabDepartment of Neurology, Emory University, Atlanta, Georgia.
Virginia J HowardDepartment of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama.
Suzanne E JuddDepartment of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama.
Emory University · USUniversity of Alabama at Birmingham · US

Funding

VCID and Stroke in a Bi-racial National CohortU01NS041588 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CUSHMAN, MARY, HOWARD, GEORGE · 2002 to 2022
$96.0M
Understanding Cohort Effects on Stroke, VCID, and Cognition After Major Epidemiologic TransitionsR01NS041588 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI MARY CUSHMAN, VIRGINIA J. HOWARD · 2001 to 2026
$8.8M
NINDS NIH HHS R01 NS041588NINDS NIH HHS U01 NS041588
6 · The paper itself

Abstract

backgroundWe investigated the association between family history of stroke (FHS) and Life's Simple 7 (LS7), a public health metric defined by the American Heart Association.

methodsReasons for Geographic and Racial Differences in Stroke is a national population-based cohort of 30,239 blacks and whites, aged 45 years or older, sampled from the US population between 2003 and 2007. Data were collected by telephone, mail questionnaires, and in-home examinations. FHS was defined as any first-degree relative with stroke. Levels of the LS7 components (total cholesterol, blood pressure, fasting glucose, physical activity, diet, smoking, and body mass index) were each coded as poor (0 points), intermediate (1 point), or ideal (2 points) health. Ordinal logistic regression was used to model the data.

resultsAmong 20,567 subjects with complete LS7 and FHS data, there were 7702 (37%) participants with an FHS. The mean age of the participants was 64 years. The mean (± standard deviation) overall LS7 score was lower for blacks (6.5 ± 2.0) than that of whites (7.6 ± 2.1). FHS was associated with poorer levels of physiological factors, particularly high blood pressure (odds ratio [OR], 1.13; 95% confidence interval [CI], 1.07-1.19) and inversely associated with behaviors such as smoking (OR, .92; 95% CI, .85-.99).

conclusionsOur results suggest that screening for FHS can provide an opportunity for earlier detection and management of modifiable risk factors.

Indexed as

Life StyleAgedAged, 80 and overBlack or African AmericanBlack PeopleBlood PressureBody Mass IndexCardiovascular DiseasesDietFemaleHealth StatusHealth SurveysHumansMaleMiddle AgedRisk FactorsCohort StudyFamily history of strokeLife Simple 7Racial Differencesrisk factors

Identifiers

PMID25497723
PMCPMC4315691
OpenAlexW2147330480

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.