Evidence map›Paper›PMID 25497060›Full record

ArticleMethods (San Diego, Calif.)2015

Selective autophagy: xenophagy.

Kyle A Bauckman, Nana Owusu-Boaitey, Indira U Mysorekar

Abstract read
In one paragraph

Article in Methods (San Diego, Calif.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed.

  1. Where and how do mammalian cells shape autophagosomes?The Journal of biological chemistry · 2026
    Review
  2. Review
  3. Autophagy in the liver.Autophagy reports · 2026
    Review
  4. Autophagy is essential for anti-Frontiers in microbiology · 2026
    Article
  5. mBio · 2025
    Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Virulence · 2023
    Article
  12. Review
  13. Article
  14. Review
  15. In situ snapshots along a mammalian selective autophagy pathway.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  16. Autophagy in Inflammatory Response against SARS-CoV-2.International journal of molecular sciences · 2023
    Review
  17. Review
  18. Article
  19. Review
  20. Review

14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kyle A BauckmanDepartment of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, MO, USA.
Nana Owusu-BoaiteyDepartment of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, MO, USA.
Indira U MysorekarDepartment of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, MO, USA; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA. Electronic address: indira@wustl.edu.

Funding

Infectious Diseases/Basic Microbial Pathogenic MechanismsT32AI007172 · NIAID · WASHINGTON UNIVERSITY · PI Daniel E. Goldberg, JENNIFER A PHILIPS · 1985 to 2026
$13.0M
Training in Reproductive SciencesT32HD049305 · NICHD · WASHINGTON UNIVERSITY · PI MOLEY, KELLE H · 2005 to 2015
$1.9M
ATG16L1 AND MOLECULAR REGULATION OF BACTERIAL PERSISTENCER01DK100644 · NIDDK · WASHINGTON UNIVERSITY · PI MYSOREKAR, INDIRA U · 2013 to 2017
$1.7M
NIAID NIH HHS T32 AI007172NIAID NIH HHS T32 AI 007172-35NICHD NIH HHS T32 HD049305NIDDK NIH HHS R01 DK100644
6 · The paper itself

Abstract

Xenophagy is an autophagic phenomenon that specifically involves pathogens and other non-host entities. Although the understanding of the relationship between autophagosomes and invading organisms has grown significantly in the past decade, the exact steps to confirm xenophagy has been not been thoroughly defined. Here we describe a methodical approach to confirming autophagy, its interaction with bacterial invasion, as well as the specific type of autophagic formation (i.e. autophagosome, autolysosome, phagolysosome). Further, we argue that xenophagy is not limited to pathogen interaction with autophagosome, but also non-microbial entities such as iron.

Indexed as

AutophagyBrucellaHost-Pathogen InteractionsHumansInfectionsLysosomesMolecular BiologyPhagosomesFerritinophagyInfectionInflammasomeLC3 Associated PhagocytosisSymbiophagyUPEC

Identifiers

PMID25497060
PMCPMC4355331

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.