ArticleBMC genomics2014
Extensive duplication of the Wolbachia DNA in chromosome four of Drosophila ananassae.
Article in BMC genomics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed.
- Evolutionary persistence of a highly prevalent multicopy mitochondrial-derived nuclear insertion (Mega-NUMT) in Neotropical Drosophila flies.Molecular biology and evolution · 2026Article
- Ghosts of symbionts past: the hidden history of the dynamic association between filarial nematodes and their Wolbachia endosymbionts.G3 (Bethesda, Md.) · 2025Article
- Suppression of cytoplasmic incompatibility in the leaf-mining flyRoyal Society open science · 2025Article
- The genome of the solitary bee Tetrapedia diversipes (Hymenoptera, Apidae).G3 (Bethesda, Md.) · 2025Article
- A Light in the Dark: Uncovering Wolbachia-Host Interactions Using Fluorescence Imaging.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Long-read genome assemblies for the study of chromosome expansion: Drosophila kikkawai, Drosophila takahashii, Drosophila bipectinata, and Drosophila ananassae.G3 (Bethesda, Md.) · 2023Article
- Long-read genome assemblies for the study of chromosome expansion:bioRxiv : the preprint server for biology · 2023Article
- Low Endosymbiont Incidence in Drosophila Species Across Peninsula Thailand.Microbial ecology · 2023Article
- Accumulation of endosymbiont genomes in an insect autosome followed by endosymbiont replacement.Current biology : CB · 2022Article
- Remnants of horizontal transfers of Wolbachia genes in a Wolbachia-free woodwasp.BMC ecology and evolution · 2022Article
- Narrow Genetic Diversity ofInternational journal of molecular sciences · 2022Article
- Ecological basis and genetic architecture of crypsis polymorphism in the desert clicker grasshopper (Ligurotettix coquilletti).Evolution; international journal of organic evolution · 2021Article
- Comparison of long-read sequencing technologies in interrogating bacteria and fly genomes.G3 (Bethesda, Md.) · 2021Article
- Prevalence and Implications of Contamination in Public Genomic Resources: A Case Study of 43 Reference Arthropod Assemblies.G3 (Bethesda, Md.) · 2020Article
- Complete Genome Sequence ofMicrobiology resource announcements · 2019Article
- Core Concept: Gene transfers from bacteria and viruses may be shaping complex organisms.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- A putative antimicrobial peptide from Hymenoptera in the megaplasmid pSCL4 ofEcology and evolution · 2019Article
- TheGenetics · 2018Article
- Functional horizontal gene transfer from bacteria to eukaryotes.Nature reviews. Microbiology · 2018Review
- The Complexities and Nuances of Analyzing the Genome ofG3 (Bethesda, Md.) · 2018Article
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Authors and funding
9 authors.
Funding
Abstract
backgroundLateral gene transfer (LGT) from bacterial Wolbachia endosymbionts has been detected in ~20% of arthropod and nematode genome sequencing projects. Many of these transfers are large and contain a substantial part of the Wolbachia genome.
resultsHere, we re-sequenced three D. ananassae genomes from Asia and the Pacific that contain large LGTs from Wolbachia. We find that multiple copies of the Wolbachia genome are transferred to the Drosophila nuclear genome in all three lines. In the D. ananassae line from Indonesia, the copies of Wolbachia DNA in the nuclear genome are nearly identical in size and sequence yielding an even coverage of mapped reads over the Wolbachia genome. In contrast, the D. ananassae lines from Hawaii and India show an uneven coverage of mapped reads over the Wolbachia genome suggesting that different parts of these LGTs are present in different copy numbers. In the Hawaii line, we find that this LGT is underrepresented in third instar larvae indicative of being heterochromatic. Fluorescence in situ hybridization of mitotic chromosomes confirms that the LGT in the Hawaii line is heterochromatic and represents ~20% of the sequence on chromosome 4 (dot chromosome, Muller element F).
conclusionsThis collection of related lines contain large lateral gene transfers composed of multiple Wolbachia genomes that constitute >2% of the D. ananassae genome (~5 Mbp) and partially explain the abnormally large size of chromosome 4 in D. ananassae.
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