Evidence map›Paper›PMID 25495675›Full record

ArticleAIDS research and human retroviruses2015

Genomic characterization of two novel HIV-1 second-generation recombinant forms among men who have sex with men in Beijing, China.

Zheng Li, Huamian Wei, Yi Feng, Jia Li, Marcia L Kalish, Hongyan Lu, Lu Yin, Lingjie Liao, Han-Zhu Qian, Simon D W Frost and 4 more

Abstract read
In one paragraph

Article in AIDS research and human retroviruses, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Zheng Li1 State Key Laboratory for Infectious Disease Prevention and Control, National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases , Beijing, China .
Huamian Wei
Yi Feng
Jia Li
Marcia L Kalish
Hongyan Lu
Lu Yin
Lingjie Liao
Han-Zhu Qian
Simon D W Frost
Yuhua Ruan
Sten H Vermund
Yiming Shao
Hui Xing

Funding

Multi-component HIV Intervention Packages for Chinese MSMR01AI094562 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI QIAN, HAN-ZHU, VERMUND, STEN H. · 2011 to 2014
$2.5M
NIAID NIH HHS R01 AI094562NIAID NIH HHS R01AI094562
6 · The paper itself

Abstract

We report two different unique HIV-1 recombinant viruses from two HIV-positive men who have sex with men (MSM) in Beijing, China. Phylogenetic analysis of near full-length genomes (NFLG) showed that the unique recombinant forms (URFs) were comprised of gene regions from two circulating recombinant forms, CRF01_AE and CRF07_BC, both common in China. The parental CRF01_AE region of the recombinants clustered together with a previously described cluster 4 lineage of CRF01_AE. The CRF07_BC regions of both the recombinants clustered within the CRF07_BC radiation, but were distinct from other CRF07_BC reference sequences. The two recombinant forms had two breakpoints in common. The emergence of the two URFs indicates the ongoing generation of recombinant viruses involving CRF01_AE and CRF07_BC, and may provide insight into our understanding of the dynamics and complexity of the HIV-1 epidemic in China.

Indexed as

Genetic VariationGenome, ViralRecombination, GeneticAdultChinaCluster AnalysisEvolution, MolecularHIV-1HIV InfectionsHomosexuality, MaleHumansMaleMolecular Sequence DataPhylogenySequence Analysis, DNASequence Homology

Identifiers

PMID25495675
PMCPMC4348344

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.