Evidence map›Paper›PMID 25495402›Full record

SynthesisBMC public health2014

The association between breastfeeding and childhood obesity: a meta-analysis.

Jing Yan, Lin Liu, Yun Zhu, Guowei Huang, Peizhong Peter Wang

Registry-linked trialAbstract readMeta-Analysis
In one paragraph

Synthesis in BMC public health, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03529630 (Breastfeeding Success With the Use of the WHO Syringe Technique for Management of Inverted Nipples in Lactating Women), which is not on this map. Cited by 336 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
336citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03529630 nacompletednot on this mapstarted 2018, after this paper: background citation

Breastfeeding Success With the Use of the WHO Syringe Technique for Management of Inverted Nipples in Lactating Women: a Study Protocol for a Randomized Controlled Trial

TypeinterventionalSponsorAmerican University of Beirut Medical CenterRan2018 to 2020Enrolled54ConditionsBreastfeeding, Inverted NippleArmsInverted syringe
3 · Its place in the literature

Who cites it

336 citing papers in PubMed, 7 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Integrative Review of Mental Health and Feeding Styles in Parents of Bottle-Fed Infants.Journal of obstetric, gynecologic, and neonatal nursing : JOGNN · 2023
    Pooled it
  4. Pooled it
  5. Diet, adiposity, and the gut microbiota from infancy to adolescence: A systematic review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2021
    Pooled it
  6. Pooled it
  7. Pooled it
  8. Trial
  9. Trial
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  11. Trial
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  13. Article
  14. Metabolic health conditions in pregnancy, human milk hormone concentrations, and infant adiposity.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  15. Article
  16. Observational
  17. Article
  18. Review
  19. Infant growth and breastfeeding patterns: The Japan Environment and Children's Study.Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology · 2026
    Article
  20. Article

276 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jing Yan
Lin Liu
Yun Zhu
Guowei HuangDivision of Community Health and Humanities, Faculty of Medicine, Memorial University of Newfoundland, St, John's, Newfoundland and Labrador A1B 3 V6, Canada. huangguowei@tmu.edu.cn.
Peizhong Peter Wang

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe increase in childhood obesity is a serious public health concern. Several studies have indicated that breastfed children have a lower risk of childhood obesity than those who were not breastfed, while other studies have provided conflicting evidence. The objective of this meta-analysis was to investigate the association between breastfeeding and the risk of childhood obesity.

methodsThe PubMed, EMBASE and CINAHL Plus with Full Text databases were systematically searched from start date to 1st August 2014. Based on the meta-analysis, pooled adjusted odds ratio (AOR) and 95% confidence interval (CI) were calculated. I2 statistic was used to evaluate the between-study heterogeneity. Funnel plots and Fail-safe N were used to assess publication bias and reliability of results, and results from both Egger test and Begg test were reported.

resultsTwenty-five studies with a total of 226,508 participants were included in this meta-analysis. The studies' publication dates ranged from 1997 to 2014, and they examined the population of 12 countries. Results showed that breastfeeding was associated with a significantly reduced risk of obesity in children (AOR = 0.78; 95% CI: 0.74, 0.81). Categorical analysis of 17 studies revealed a dose-response effect between breastfeeding duration and reduced risk of childhood obesity.

conclusionResults of our meta-analysis suggest that breastfeeding is a significant protective factor against obesity in children.

Indexed as

Breast FeedingChildHumansMalePediatric ObesityProtective FactorsRisk

Identifiers

PMID25495402
PMCPMC4301835

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.